Anti-Myeloperoxidase抗体[59A5] (ab88846)

概述

  • 产品名称Anti-Myeloperoxidase抗体[59A5]
    参阅全部 Myeloperoxidase 一抗
  • 描述
    小鼠单克隆抗体[59A5] to Myeloperoxidase
  • 特异性This antibody stains strongly with the cytoplasm of myeloid cells. The antibody detects myeloperoxidase found in myeloid cells of acute myeloid leukemia.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant protein from exon 7 of the Human Myeloperoxidase.

  • 阳性对照
    • Tonsil

性能

应用

Our Abpromise guarantee covers the use of ab88846 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: Ready to use. Sections require high temperature antigen unmasking with 10mM citrate buffer, pH 6.0 prior to immunostaining.

    Is unsuitable for IHC-Fr.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
    • 疾病相关Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
    • 序列相似性Belongs to the peroxidase family. XPO subfamily.
    • 细胞定位Lysosome.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 84 kDa myeloperoxidase antibody
      • 89 kDa myeloperoxidase antibody
      • EC 1.11.1.7 antibody
      • EC1.11.2.2 antibody
      • fj80f04 antibody
      • MPO antibody
      • mpx antibody
      • myeloid-specific peroxidase antibody
      • Myeloperoxidase antibody
      • Myeloperoxidase heavy chain antibody
      • Myeloperoxidase light chain antibody
      • PERM_HUMAN antibody
      • wu:fj80f04 antibody
      see all

    Anti-Myeloperoxidase antibody [59A5] (ab88846)参考文献

    ab88846 has not yet been referenced specifically in any publications.

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    I can confirm that a light green staining of the antibody solution in the vial is normal. ab88846 is provided as tissue culture supernatant. Therefore is contains medium including the blueish dye that indicates the pH of the medium (usually p...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"