Anti-Myeloperoxidase抗体[2D4] (Biotin) (ab90811)

概述

• 产品名称
  Anti-Myeloperoxidase抗体[2D4] (Biotin)
  参阅全部 Myeloperoxidase 一抗
• 描述
  小鼠单克隆抗体[2D4] to Myeloperoxidase (Biotin)
• 偶联物
  Biotin
• 经测试应用
  适用于: IHC-Fr, Flow Cyt, ICC/IF, IHC-Pmore details
• 种属反应性
  与反应: Mouse, Rat
  
• 免疫原

  Purified Rat Myeloperoxidase

性能

• 形式
  Liquid
• 存放说明
  Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
• 存储溶液
  Preservative: 0.02% Sodium Azide
  Constituents: 1% BSA, PBS
• Concentration information loading...
• 纯化说明
  ab90811 is 0.2 µm filtered
• 克隆
  单克隆
• 克隆编号
  2D4
• 同种型
  IgG1
• 研究领域
  • Immunology
  • Innate Immunity
  • Macrophage / Inflamm.

  • Cardiovascular
  • Blood
  • Other

  • Cardiovascular
  • Vasculature
  • Vasculature Markers
  • Arterial

  • Cardiovascular
  • Vasculature
  • Vasculature Markers
  • Pulmonary

  • Cancer
  • Cancer Metabolism
  • Cellular metabolic process

  • Kits/ Lysates/ Other
  • Kits
  • ELISA Kits
  • ELISA Kits
  • Cancer proteins ELISA kits

  • Kits/ Lysates/ Other
  • Kits
  • ELISA Kits
  • ELISA Kits
  • Cardiovascular ELISA kits

  • Metabolism
  • Pathways and Processes
  • Redox metabolism
  • Antioxidants

  • Metabolism
  • Types of disease
  • Cancer

相关产品

• Assay kits
  • Myeloperoxidase (MPO) Activity Assay Kit (Colorimetric) (ab105136)
  • Myeloperoxidase (MPO) Activity Assay Kit (Fluorometric) (ab111749)
• Compatible Secondaries
  • Goat Anti-Mouse IgG H&L (Alexa Fluor® 488) (ab150113)
  • Goat Anti-Mouse IgG H&L (HRP) (ab205719)

应用

靶标

• 功能
  Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
• 疾病相关
  Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
• 序列相似性
  Belongs to the peroxidase family. XPO subfamily.
• 细胞定位
  Lysosome.

• Target information above from: UniProt accession P05164 The UniProt Consortium
  The Universal Protein Resource (UniProt) in 2010
  Nucleic Acids Res. 38:D142-D148 (2010) .

  Information by UniProt
• 数据库链接
  • Entrez Gene: 17523 Mouse
  • Entrez Gene: 303413 Rat
  • SwissProt: P11247 Mouse
  • Unigene: 4668 Mouse
  • Unigene: 47782 Rat
• 别名
  • 84 kDa myeloperoxidase antibody
  • 89 kDa myeloperoxidase antibody
  • EC 1.11.1.7 antibody

  • EC1.11.2.2 antibody
  • fj80f04 antibody
  • MPO antibody
  • mpx antibody
  • myeloid-specific peroxidase antibody
  • Myeloperoxidase antibody
  • Myeloperoxidase heavy chain antibody
  • Myeloperoxidase light chain antibody
  • PERM_HUMAN antibody
  • wu:fj80f04 antibody

  see all

实验方案

• Flow cytometry protocols
• Immunohistochemistry protocols
• Immunocytochemistry & immunofluorescence protocols