Anti-Myeloperoxidase抗体[2D4] (Biotin) (ab90811)
- 数据表
- 具体的参考文献 (2)
- 实验方案
概述
-
产品名称Anti-Myeloperoxidase抗体[2D4] (Biotin)
参阅全部 Myeloperoxidase 一抗 -
描述小鼠单克隆抗体[2D4] to Myeloperoxidase (Biotin)
-
宿主Mouse
-
偶联物Biotin
-
经测试应用适用于: IHC-Fr, Flow Cyt, ICC/IF, IHC-Pmore details
-
种属反应性与反应: Mouse, Rat
-
免疫原
Purified Rat Myeloperoxidase
性能
-
形式Liquid
-
存放说明Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
-
存储溶液Preservative: 0.02% Sodium Azide
Constituents: 1% BSA, PBS -
Concentration information loading... -
纯化说明ab90811 is 0.2 µm filtered
-
克隆单克隆
-
克隆编号2D4
-
同种型IgG1
-
研究领域
相关产品
-
Alternative Versions
-
Assay kits
-
Compatible Secondaries
应用
Our Abpromise guarantee covers the use of ab90811 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
| 应用 | Ab评论 | 说明 |
|---|---|---|
| IHC-Fr | 1/50. | |
| Flow Cyt | 1/50. ab18434 - Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
|
|
| ICC/IF | Use at an assay dependent concentration. | |
| IHC-P | Use at an assay dependent concentration. PubMed: 23817216 |
靶标
-
功能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
-
疾病相关Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
-
序列相似性Belongs to the peroxidase family. XPO subfamily.
-
细胞定位Lysosome.
- Information by UniProt
-
数据库链接
- Entrez Gene: 17523 Mouse
- Entrez Gene: 303413 Rat
- SwissProt: P11247 Mouse
- Unigene: 4668 Mouse
- Unigene: 47782 Rat
-
别名
- 84 kDa myeloperoxidase antibody
- 89 kDa myeloperoxidase antibody
- EC 1.11.1.7 antibody
see all
实验方案
文献
This product has been referenced in:
- Ramachandran M et al. An infection-enhanced oncolytic adenovirus secreting H. pylori neutrophil-activating protein with therapeutic effects on neuroendocrine tumors. Mol Ther 21:2008-18 (2013). IHC-P ; Mouse . Read more (PubMed: 23817216) »
- Deng Z et al. Plant homologue constitutive photomorphogenesis 9 (COP9) signalosome subunit CSN5 regulates innate immune responses in macrophages. Blood 117:4796-804 (2011). IHC ; Mouse . Read more (PubMed: 21403132) »
客户评价及客户问答
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"