Anti-Myeloperoxidase抗体[2D4] (ab90810)

概述

  • 产品名称Anti-Myeloperoxidase抗体[2D4]
    参阅全部 Myeloperoxidase 一抗
  • 描述
    小鼠单克隆抗体[2D4] to Myeloperoxidase
  • 经测试应用适用于: IHC-Fr, Flow Cyt, ICC/IF, ELISAmore details
    不适用于: IHC-P or WB
  • 种属反应性
    与反应: Mouse, Rat
  • 免疫原

    Antigen used is purified natural MPO.

性能

应用

Our Abpromise guarantee covers the use of ab90810 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-Fr 1/50.
Flow Cyt 1/50. ab170190-Mouse monoclonal IgG1, is suitable for use as an isotype control with this antibody.
ICC/IF 1/50.
ELISA Use at an assay dependent concentration.
  • 应用说明Is unsuitable for IHC-P or WB.
  • 靶标

    • 功能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
    • 疾病相关Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
    • 序列相似性Belongs to the peroxidase family. XPO subfamily.
    • 细胞定位Lysosome.
    • Information by UniProt
    • 数据库链接
    • 别名
      • 84 kDa myeloperoxidase antibody
      • 89 kDa myeloperoxidase antibody
      • EC 1.11.1.7 antibody
      • EC1.11.2.2 antibody
      • fj80f04 antibody
      • MPO antibody
      • mpx antibody
      • myeloid-specific peroxidase antibody
      • Myeloperoxidase antibody
      • Myeloperoxidase heavy chain antibody
      • Myeloperoxidase light chain antibody
      • PERM_HUMAN antibody
      • wu:fj80f04 antibody
      see all

    Anti-Myeloperoxidase antibody [2D4] 图像

    • ab90810 at 1/50 dilution staining Myeloperoxidase in rat white blood cells by Immunocytochemistry/ Immunofluorescence. Image shows green staining with ab90810 in neutrophils and monocytes.

    Anti-Myeloperoxidase antibody [2D4] (ab90810)参考文献

    ab90810 has not yet been referenced specifically in any publications.

    Product Wall

    Abcam has not validated the combination of species/application used in this Abreview.
    Application Immunocytochemistry/ Immunofluorescence
    Sample Sheep Cell (Lung)
    Specification Lung
    Fixative Formaldehyde
    Blocking step Serum as blocking agent for 1 hour(s) and 0 minute(s) · Concentration: 10% · Temperature: RT°C
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    提交于 May 13 2013

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    Myeloperoxidase is known to be expressed in a subset of lymphoid cells. Tissues known to express this protein include spleen, lymph node and heatopoietic cells of bone marrow.Any of these...

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"