概述

  • 产品名称Anti-Myeloperoxidase抗体[1A1]
    参阅全部 Myeloperoxidase 一抗
  • 描述
    小鼠单克隆抗体[1A1] to Myeloperoxidase
  • 经测试应用适用于: IP, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length native protein purified from Human sputum

  • 阳性对照
    • HL-60 cell lysate

性能

应用

Our Abpromise guarantee covers the use of ab51065 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at an assay dependent dilution. Use 2µg for 400µl lysate.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Part of the host defense system of polymorphonuclear leukocytes. It is responsible for microbicidal activity against a wide range of organisms. In the stimulated PMN, MPO catalyzes the production of hypohalous acids, primarily hypochlorous acid in physiologic situations, and other toxic intermediates that greatly enhance PMN microbicidal activity.
  • 疾病相关Defects in MPO are the cause of myeloperoxidase deficiency (MPD) [MIM:254600]. MPD is an autosomal recessive defect that results in disseminated candidiasis.
  • 序列相似性Belongs to the peroxidase family. XPO subfamily.
  • 细胞定位Lysosome.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 84 kDa myeloperoxidase antibody
    • 89 kDa myeloperoxidase antibody
    • EC 1.11.1.7 antibody
    • EC1.11.2.2 antibody
    • fj80f04 antibody
    • MPO antibody
    • mpx antibody
    • myeloid-specific peroxidase antibody
    • Myeloperoxidase antibody
    • Myeloperoxidase heavy chain antibody
    • Myeloperoxidase light chain antibody
    • PERM_HUMAN antibody
    • wu:fj80f04 antibody
    see all

Anti-Myeloperoxidase antibody [1A1] 图像

  • Immunoprecipitation analysis of HL-60 cell lysate with ab51065 at 2µg for 400µl of lysate. Lane 1: Input; Lane 2: Precipitates. Western blot detection was done with ab76100.

Anti-Myeloperoxidase antibody [1A1] (ab51065)参考文献

This product has been referenced in:
  • Silvescu CI & Sackstein R G-CSF induces membrane expression of a myeloperoxidase glycovariant that operates as an E-selectin ligand on human myeloid cells. Proc Natl Acad Sci U S A 111:10696-701 (2014). IP ; Human . Read more (PubMed: 25002508) »
  • Huang Y  et al. Myeloperoxidase, paraoxonase-1, and HDL form a functional ternary complex. J Clin Invest 123:3815-28 (2013). IP ; Human . Read more (PubMed: 23908111) »

See all 2 Publications for this product

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