Anti-Mycobacterium tuberculosis RV2031抗体[31C11] (ab64786)

概述

  • 产品名称
    Anti-Mycobacterium tuberculosis RV2031抗体[31C11]
  • 描述
    小鼠单克隆抗体[31C11] to Mycobacterium tuberculosis RV2031
  • 特异性
    This antibody recognises an amino acid sequence corresponding to the Rv2031 gene.
  • 经测试应用
    适用于: Indirect ELISA, WBmore details
  • 种属反应性
    Reacts with Mycobacterium tuberculosis, RV2031 dormant protein from H37Rv strain.
  • 免疫原

    Recombinant full length protein: Rv2031.

  • 常规说明

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: PBS, pH 7.4
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 克隆
    单克隆
  • 克隆编号
    31C11
  • 骨髓瘤
    Sp2/0
  • 同种型
    IgG1
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab64786 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
Indirect ELISA Use at an assay dependent dilution.
WB Use at an assay dependent dilution.

靶标

  • 相关性
    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
  • 别名
    • RV2031 antibody

实验方案

Anti-Mycobacterium tuberculosis RV2031 antibody [31C11] (ab64786)参考文献

This product has been referenced in:
  • Shi C  et al. Enhanced protection against tuberculosis by vaccination with recombinant BCG over-expressing HspX protein. Vaccine 28:5237-44 (2010). Read more (PubMed: 20538090) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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