Anti-Mycobacterium tuberculosis抗体(Biotin) (ab20027)

概述

  • 产品名称
    Anti-Mycobacterium tuberculosis抗体(Biotin)
    参阅全部 Mycobacterium tuberculosis 一抗
  • 描述
    兔多克隆抗体to Mycobacterium tuberculosis (Biotin)
  • 偶联物
    Biotin
  • 特异性
    Minimum of two major M. tuberculosis bands by immunoelectrophoresis (gamma & beta).
  • 经测试应用
    适用于: IHC-Pmore details
  • 种属反应性
    Reacts with Mycobacteria species including M. avium, M. phlei and M. parafortuitum. Does not react with E. coli K12, Salmonella typhimurium, Pseudomonas aeruginosa, Streptococcus (group B), Candida albicans and Neisseria meningitidis. Not yet tested in other species.
  • 免疫原

    Purified Protein Derivative (used for Tb skin testing)

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Store at -20°C or -80°C. Avoid freeze / thaw cycle.
  • 存储溶液
    Preservative: 0.1% Sodium Azide
    Constituents: 0.01M PBS, pH 7.2
  • Concentration information loading...
  • 纯度
    Protein G purified
  • 纯化说明
    IgG fraction covalently coupled with the N-Hydroxysuccinimide ester of biotin under mild conditions to give a high degree of substitution.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab20027 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P Use at an assay dependent dilution. Do not perform antigen retrieval.

靶标

  • 相关性
    Mycobacterium tuberculosis is the most common cause of tuberculosis. Primary infection begins with inhalation of 1 to 10 aerosolised bacilli. The pathogenicity of the organism is determined by its ability to escape host immune responses as well as eliciting delayed hypersensitivity. Alveolar macrophages engulf the invading cells but are unable to mount an effective defense. Several virulence factors are responsible for this apparent failure; most notably in the mycobacterial cell wall are the cord factor, lipoarabinomannan, and the 65 kd heat shock protein or HSP65. The emergence of new strains of resistant Mycobacterium tuberculosis has created new interest in clinical diagnosis. Studies have shown immunohistochemical techniques to be superior to conventional special stains. Thus the demonstration of mycobacterial antigens are not only useful in establishing mycobacterial aetiology, but can also be used as an alternative method to the conventional Ziehl-Neelsen method.
  • 别名
    • M. tuberculosis antibody

文献

ab20027 has not yet been referenced specifically in any publications.

客户评价及客户问答

Thank you for your enquiry. I regret to inform you that the originator of this antibody no longer has sufficient stocks for us to be able to make this product available to our customers. We have therefore been forced to withdraw ab34957 from our pr...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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