Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.02% Sodium Azide
Constituents: 0.5% BSA, Tris buffered saline, pH 7.3
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Immunogen affinity purified
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/0.1 - 1/0.3. Detects a band of approximately 85 kDa (predicted molecular weight: 60 kDa). PubMed: 17272810
Use at an assay dependent dilution.
May regulate gene expression and protein turnover in muscle cells.
Highly expressed in muscle. Low-level expression in liver.
Contains 1 B box-type zinc finger.
Contains 1 COS domain. Contains 1 RING-type zinc finger.
Cytoplasm. Nucleus. Nuclear under atrophic conditions and upon mechanical signals. Localizes to the sarcomeric M-band in cardiomyocytes. Colocalizes in part with microtubules.
Information by UniProt
MURF 2 antibody
Anti-MURF2 antibody (ab4387)参考文献
This product has been referenced in:
et al. MuRF2 regulates PPAR?1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet. Cardiovasc Diabetol 14:97 (2015).
Read more (PubMed: 26242235) »
et al. Developmental regulation of MURF ubiquitin ligases and autophagy proteins nbr1, p62/SQSTM1 and LC3 during cardiac myofibril assembly and turnover. Dev Biol 351:46-61 (2011).
Read more (PubMed: 21185285) »
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for this product
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"