Anti-Munc18c抗体(ab112934)

概述

  • 产品名称Anti-Munc18c抗体
    参阅全部 Munc18c 一抗
  • 描述
    兔多克隆抗体to Munc18c
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region between internal sequence amino acids 144-171 of Human Munc18c (NP_009200.2)

  • 阳性对照
    • SK-BR-3 cell line lysates

性能

应用

Our Abpromise guarantee covers the use of ab112934 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 68 kDa.

靶标

  • 功能Together with STX4 and VAMP2, may play a role in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes.
  • 组织特异性Megakaryocytes and platelets.
  • 序列相似性Belongs to the STXBP/unc-18/SEC1 family.
  • 翻译后修饰Phosphorylated by PKC in platelets in response to thrombin stimulation; phosphorylation inhibits binding to STX4.
  • 细胞定位Cytoplasm > cytosol. Cell membrane. In platelets, predominantly cytosolic. Low amounts membrane-associated.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Munc18 3 antibody
    • Munc18 c antibody
    • Platelet Sec1 protein antibody
    • Protein unc-18 homolog 3 antibody
    • Protein unc-18 homolog C antibody
    • PSP antibody
    • STXB3_HUMAN antibody
    • STXBP 3 antibody
    • STXBP3 antibody
    • Sxtbp3 antibody
    • syntaxin 4 binding protein antibody
    • Syntaxin binding protein 3 antibody
    • Syntaxin-binding protein 3 antibody
    • Unc 18 3 antibody
    • Unc 18 homolog 3 antibody
    • Unc 18c antibody
    • Unc-18C antibody
    • Unc18-3 antibody
    see all

Anti-Munc18c antibody 图像

  • Anti-Munc18c antibody (ab112934) at 1/100 dilution + SK-BR-3 cell line lysates at 35 µg

    Predicted band size : 68 kDa

Anti-Munc18c antibody (ab112934)参考文献

ab112934 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam. We do not have data on whether ab112934 does recognize other members of the Munc18 family, but the region that was used as the peptide sequence has a very low level of homology with the other family members and I think i...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"