概述

  • 产品名称Anti-MUM1抗体
    参阅全部 MUM1 一抗
  • 描述
    小鼠多克隆抗体to MUM1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length human protein

  • 阳性对照
    • FLJ14868-transfected 293T cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 1X PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab69220 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 79 kDa.

靶标

  • 功能Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage.
  • 序列相似性Belongs to the MUM1 family.
    Contains 1 PWWP domain.
  • 结构域The PWWP domain mediates the interaction with nucleosomes.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Nucleus. Recuited to DNA damage sites via its interaction with the BRCT domain of TP53BP1.
  • Information by UniProt
  • 数据库链接
  • 别名
    • EXPAND1 antibody
    • FLJ14868 antibody
    • FLJ22283 antibody
    • HSPC211 antibody
    • Melanoma associated antigen (mutated) 1 antibody
    • Melanoma ubiquitous mutated protein antibody
    • MGC131891 antibody
    • MGC163315 antibody
    • MUM 1 antibody
    • MUM-1 antibody
    • MUM1 antibody
    • MUM1_HUMAN antibody
    • Mutated melanoma associated antigen 1 antibody
    • Mutated melanoma-associated antigen 1 antibody
    • Protein expandere antibody
    • PWWP domain containing protein MUM1 antibody
    • PWWP domain-containing protein MUM1 antibody
    see all

Anti-MUM1 antibody 图像

  • All lanes : Anti-MUM1 antibody (ab69220) at 1/500 dilution

    Lane 1 : MUM1 transfected 293T cell lysate
    Lane 2 : Non-transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP conjugated at 1/2500 dilution

    Predicted band size : 79 kDa
    Observed band size : 90 kDa (why is the actual band size different from the predicted?)

Anti-MUM1 antibody (ab69220)参考文献

ab69220 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"