概述

  • 产品名称
    Anti-Mucolipin 1抗体
  • 描述
    兔多克隆抗体to Mucolipin 1
  • 经测试应用
    适用于: ELISA, WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Guinea pig, Cow, Cat, Dog, Pig, Cynomolgus monkey
  • 免疫原

    Synthetic peptide (Human) corresponding to a 14 amino acid sequence within residues 101-150 of Human Mucolipin 1.

  • 阳性对照
    • Jurkat Cell Lysate.

性能

  • 形式
    Liquid
  • 存放说明
    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
  • 存储溶液
    Preservative: None
    Constituents: 2% Sucrose, PBS.
  • Concentration information loading...
  • 纯度
    Immunogen affinity purified
  • 纯化说明
    This antibody is purified by peptide affinity chromatography method.
  • 克隆
    多克隆
  • 同种型
    IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab28508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA 1/62500.
WB Use a concentration of 0.5 µg/ml. Predicted molecular weight: 64 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能
    Cation channel probably playing a role in the endocytic pathway and in the control of membrane trafficking of proteins and lipids. Could play a major role in Ca(2+) transport regulating lysosomal exocytosis.
  • 组织特异性
    Widely expressed in adult and fetal tissues.
  • 疾病相关
    Mucolipidosis 4
  • 序列相似性
    Belongs to the transient receptor (TC 1.A.4) family. Polycystin subfamily. MCOLN1 sub-subfamily.
  • 细胞定位
    Cell membrane. Late endosome membrane. Lysosome membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MCLN1_HUMAN antibody
    • Mcoln 1 antibody
    • Mcoln1 antibody
    • MG 2 antibody
    • MG-2 antibody
    • MG2 antibody
    • ML 4 antibody
    • ML4 antibody
    • MLIV antibody
    • MST080 antibody
    • MSTP080 antibody
    • Mucolipidin antibody
    • Mucolipin-1 antibody
    • Mucolipin1 antibody
    • TRP ML1 antibody
    • TRPML1 antibody
    see all

图片

  • Anti-Mucolipin 1 antibody (ab28508) at 0.5 µg/ml + Jurkat cell lysate

    Secondary
    Rabbit Anti mucolipin 1 at 1/50000 dilution

    Predicted band size : 64 kDa

实验方案

文献

This product has been referenced in:
  • Zhang F  et al. TRP-ML1 functions as a lysosomal NAADP-sensitive Ca2+ release channel in coronary arterial myocytes. J Cell Mol Med 13:3174-85 (2009). Read more (PubMed: 18754814) »

See 1 Publication for this product

客户评价及客户问答

Thank you for your reply.

All of the antibodies suggested have successfully been used in WB with Human samples. They should all work in such application.

All the references we have about our products are listed on the datasheets. Un...

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Thank you for contacting us.

There are seven options available to target Mucolipin 1 with WB; however, depending on the species and the sequence of the peptide used as an immunogen, some of the options may be more convenient than others.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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