Anti-MUC7抗体[4D2-1D7] (ab105466)

概述

  • 产品名称Anti-MUC7抗体[4D2-1D7]
    参阅全部 MUC7 一抗
  • 描述
    小鼠单克隆抗体[4D2-1D7] to MUC7
  • 特异性No cross reactivity with other Human mucins.
  • 经测试应用适用于: ELISA, IHC-P, WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    EGRERDHELRHRRHHHQ

    conjugated to KLH, corresponding to N terminal amino acids 21-37 of Human MUC7

  • 常规说明Growth Conditions: Cell were grown in IMDM medium containing hypoxanthine, aminopterin, thymidine, 20% FCS and 10% Domadrive.

性能

应用

Our Abpromise guarantee covers the use of ab105466 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA Use at an assay dependent concentration.
IHC-P Use at an assay dependent concentration.
WB Use at an assay dependent concentration. Predicted molecular weight: 39 kDa.

靶标

  • 功能May function in a protective capacity by promoting the clearance of bacteria in the oral cavity and aiding in mastication, speech, and swallowing. Binds P.aeruginosa pili.
  • 组织特异性Expressed in salivary gland tissues and only in those that contain mucous acinar cells (e.g. sublingual and submandibular glands) and not in salivary glands containing only serous acinar cells (e.g. parotid gland).
  • 疾病相关Genetic variations in MUC7 are associated with susceptibility to asthma (ASTHMA) [MIM:600807]. The most common chronic disease affecting children and young adults. It is a complex genetic disorder with a heterogeneous phenotype, largely attributed to the interactions among many genes and between these genes and the environment. It is characterized by recurrent attacks of paroxysmal dyspnea, with weezing due to spasmodic contraction of the bronchi.
  • 翻译后修饰N- and O-glycosylated. Contains fucose, mannose, galactose, N-acetylglucosamine and N-acetylgalactosamine.
  • 细胞定位Secreted.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Apo MG2 antibody
    • Apo-MG2 antibody
    • DKFZp686J03256 antibody
    • FLJ27047 antibody
    • MG2 antibody
    • MGC34772 antibody
    • MUC 7 antibody
    • MUC-7 antibody
    • MUC7 antibody
    • MUC7_HUMAN antibody
    • Mucin 7 antibody
    • Mucin 7, salivary antibody
    • Mucin 7, secreted antibody
    • Mucin-7 antibody
    • Salivary mucin 7 antibody
    • Salivary mucin-7 antibody
    see all

Anti-MUC7 antibody [4D2-1D7] (ab105466)参考文献

ab105466 has not yet been referenced specifically in any publications.

Product Wall

Thank you for contacting Abcam.   I have attached the MSDS for ab97120 and ab97105, both of which contain the preservative proclin.  A MSDS is not required for ab105466.   I hope this information is helpful.  Please do not hesitate to contact us if you...

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