产品名称 Anti-MUC20抗体 参阅全部 MUC20 一抗
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Full length protein, corresponding to amino acids 1-538 of Human MUC20 (AAH44243)
MUC20 transfected 293T cell lysate
存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: None
Constituents: PBS, pH 7.2
Concentration information loading...
纯度 Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/500 - 1/1000. Predicted molecular weight: 72 kDa.
功能 May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
组织特异性 Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
细胞定位 Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane.
Information by UniProt
MUC 20 antibody
Anti-MUC20 antibody 图像
Western blot - MUC20 antibody (ab73043)
All lanes : Anti-MUC20 antibody (ab73043) at 1/500 dilution Lane 1 : MUC20 transfected 293T cell lysate Lane 2 : Non transfected 293T cell lysate Lysates/proteins at 25 µg per lane. Secondary Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution developed using the ECL technique Predicted band size : 72 kDa Observed band size : 80 kDa ( why is the actual band size different from the predicted?)
Anti-MUC20 antibody (ab73043)参考文献
has not yet been referenced specifically in any publications.
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