概述

  • 产品名称Anti-MUC20抗体
    参阅全部 MUC20 一抗
  • 描述
    小鼠多克隆抗体to MUC20
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Full length protein, corresponding to amino acids 1-538 of Human MUC20 (AAH44243)

  • 阳性对照
    • MUC20 transfected 293T cell lysate

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein A purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab73043 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 72 kDa.

靶标

  • 功能May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
  • 组织特异性Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
  • 细胞定位Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection > microvillus membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MUC 20 antibody
    • MUC-20 antibody
    • Muc20 antibody
    • MUC20_HUMAN antibody
    • Mucin 20 antibody
    • Mucin 20, cell surface associated antibody
    • Mucin-20 antibody
    • Transmembrane mucin MUC20S antibody
    see all

Anti-MUC20 antibody 图像

  • All lanes : Anti-MUC20 antibody (ab73043) at 1/500 dilution

    Lane 1 : MUC20 transfected 293T cell lysate
    Lane 2 : Non transfected 293T cell lysate

    Lysates/proteins at 25 µg per lane.

    Secondary
    Goat Anti-Mouse IgG (H&L)-HRP Conjugate at 1/5000 dilution
    Developed using the ECL technique

    Predicted band size : 72 kDa
    Observed band size : 80 kDa (why is the actual band size different from the predicted?)

Anti-MUC20 antibody (ab73043)参考文献

ab73043 has not yet been referenced specifically in any publications.

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