概述

  • 产品名称Anti-MTUS1抗体
    参阅全部 MTUS1 一抗
  • 描述
    兔多克隆抗体to MTUS1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    A 14-22 amino acid region within synthetic peptide: EALTVVIQHL LSEREEALKQ HKTLSQELVN LRGELVTAST TCEKLEKARN, corresponding to internal sequence amino acids 181-230 of Human MTUS1

  • 阳性对照
    • Jurkat cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab61309 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1.25 µg/ml. Detects a band of approximately 44 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 相关性Multiple alternatively spliced transcript variants encoding different isoforms have been found for the MTUS1 (Mitochondrial tumor suppressor 1) gene. One of the transcript variants has been shown to encode a mitochondrial protein that acts as a tumor suppressor and cooperates with the angiotension II (AT2) receptor (AGTR2) to inhibit ERK2 activation and cell proliferation. MTUS1 polypeptides are identical in their carboxy-terminal region carrying four coiled-coil domains. In their amino-terminal portion, MTUS1 polypeptides exhibit distinct motifs for localisation in the cytosol, nucleus or cell membrane, suggesting that MTUS1 gene products may be involved in a variety of intracellular functions in an AT2-dependent and independent manner.
  • 细胞定位Cell Membrane, Golgi Apparatus, Mitochondrial and Nuclear. Note=In neurons, translocates into the nucleus after treatment with angiotensin-II.
  • 数据库链接
  • 别名
    • AGTR2-interacting protein antibody
    • Angiotensin II type 2 receptor interacting protein antibody
    • AT2 receptor interacting protein antibody
    • AT2 receptor-binding protein antibody
    • AT2R binding protein antibody
    • ATBP antibody
    • ATIP antibody
    • ATIP1 antibody
    • DKFZp586D1519 antibody
    • DKFZp686F20243 antibody
    • Erythroid differentiation related antibody
    • FLJ14295 antibody
    • GK 1 antibody
    • GK1 antibody
    • KIAA1288 antibody
    • Microtubule associated tumor suppressor 1 antibody
    • Mitochondrial tumor suppressor 1 antibody
    • Mitochondrial tumor suppressor gene 1 antibody
    • MP 44 antibody
    • MP44 antibody
    • MTSG 1 antibody
    • MTSG1 antibody
    • MTUS 1 antibody
    • Transcription factor MTSG1 antibody
    see all

Anti-MTUS1 antibody 图像

  • Anti-MTUS1 antibody (ab61309) at 1.25 µg/ml + Jurkat cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Observed band size : 44 kDa (why is the actual band size different from the predicted?)
  • All lanes : Anti-MTUS1 antibody (ab61309) at 1/200 dilution

    Lane 1 : Whole cell lysate prepared from MCF cells transfected with GFP-ATIP1
    Lane 2 : Whole cell lysate prepared from MCF cells transfected with GFP-ATIP3
    Lane 3 : Whole cell lysate prepared from MCF cells transfected with GFP

Anti-MTUS1 antibody (ab61309)参考文献

ab61309 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab61309.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"