概述

  • 产品名称Anti-MTGR1抗体
    参阅全部 MTGR1 一抗
  • 描述
    兔多克隆抗体to MTGR1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Horse, Chicken, Guinea pig, Cow, Cat, Dog
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 554-603 GQGRPLLPVGRGSSARSADCSVPSPALDKTSATTSRSSTPASVTAIDTNG of Human MTGR1 (NP_005084).

  • 阳性对照
    • Human fetal thymus lysate.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    Constituents: 2% Sucrose, PBS
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab98172 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 67 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
  • 组织特异性Ubiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus.
  • 序列相似性Belongs to the CBFA2T family.
    Contains 1 MYND-type zinc finger.
    Contains 1 TAFH (NHR1) domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AML1 MTG8 antibody
    • cbfa2t2 antibody
    • Core binding factor runt domain alpha subunit 2 translocated to 2 antibody
    • core-binding factor, runt domain, alpha subunit 2 antibody
    • DKFZp313F2116 antibody
    • EHT antibody
    • ETO homolog on chromosome 20 antibody
    • ETO homologous on chromosome 20 antibody
    • MTG 8 like protein antibody
    • MTG 8 related protein 1 antibody
    • MTG8 like protein antibody
    • MTG8 related protein 1 antibody
    • MTG8-like protein antibody
    • MTG8-related protein 1 antibody
    • MTG8R_HUMAN antibody
    • MTGR 1 antibody
    • Myeloid translocation gene related protein 1 antibody
    • Myeloid translocation related protein 1 antibody
    • Myeloid translocation-related protein 1 antibody
    • p85 antibody
    • Protein CBFA2T2 antibody
    • ZMYND 3 antibody
    • ZMYND3 antibody
    see all

Anti-MTGR1 antibody 图像

  • Anti-MTGR1 antibody (ab98172) at 1 µg/ml (5% skim milk / PBS buffer) + Human fetal thymus lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50,000

    Predicted band size : 67 kDa

Anti-MTGR1 antibody (ab98172)参考文献

ab98172 has not yet been referenced specifically in any publications.

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