概述

  • 产品名称Anti-MTGR1抗体
    参阅全部 MTGR1 一抗
  • 描述
    兔多克隆抗体to MTGR1
  • 经测试应用适用于: WB, ICC/IFmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Recombinant protein fragment corresponding to a region within amino acids 401 and 598 of Human MTGR1.

  • 阳性对照
    • 293T, A431, H1299, HeLa, HepG2, Molt-4, Raji cell lysate. HeLa cells for IF.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: 0.01% Thimerosal (merthiolate)
    Constituents: 10% Glycerol, 0.1M Tris, 0.1M Glycine, pH 7
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab96161 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/3000. Predicted molecular weight: 67 kDa.
ICC/IF 1/100 - 1/200.

靶标

  • 功能May function as a complex with the chimeric protein RUNX1/AML1-CBFA2T1/MTG8 which is produced in acute myeloid leukemia with the chromosomal translocation t(8;21). May thus be involved in the repression of AML1-dependent transcription and the induction of G-CSF/CSF3-dependent cell growth. May be a tumor suppressor gene candidate involved in myeloid tumors with the deletion of the 20q11 region.
  • 组织特异性Ubiquitously expressed in fetal and adult tissues. Highly expressed in adult brain, heart, lung, kidney, lymph node, appendix, thymus, testis, uterus, small intestine, prostate and thymus.
  • 序列相似性Belongs to the CBFA2T family.
    Contains 1 MYND-type zinc finger.
    Contains 1 TAFH (NHR1) domain.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • AML1 MTG8 antibody
    • cbfa2t2 antibody
    • Core binding factor runt domain alpha subunit 2 translocated to 2 antibody
    • core-binding factor, runt domain, alpha subunit 2 antibody
    • DKFZp313F2116 antibody
    • EHT antibody
    • ETO homolog on chromosome 20 antibody
    • ETO homologous on chromosome 20 antibody
    • MTG 8 like protein antibody
    • MTG 8 related protein 1 antibody
    • MTG8 like protein antibody
    • MTG8 related protein 1 antibody
    • MTG8-like protein antibody
    • MTG8-related protein 1 antibody
    • MTG8R_HUMAN antibody
    • MTGR 1 antibody
    • Myeloid translocation gene related protein 1 antibody
    • Myeloid translocation related protein 1 antibody
    • Myeloid translocation-related protein 1 antibody
    • p85 antibody
    • Protein CBFA2T2 antibody
    • ZMYND 3 antibody
    • ZMYND3 antibody
    see all

Anti-MTGR1 antibody 图像

  • Anti-MTGR1 antibody (ab96161) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

    Predicted band size : 67 kDa
  • Top panel: immunofluorescence analysis of paraformaldehyde-fixed HeLa cells, using ab96161 at 1/200 dilution.
    Bottom panel: image merged with DNA probe.

Anti-MTGR1 antibody (ab96161)参考文献

This product has been referenced in:
  • Nady N  et al. ETO family protein Mtgr1 mediates Prdm14 functions in stem cell maintenance and primordial germ cell formation. Elife 4:e10150 (2015). Read more (PubMed: 26523391) »

See 1 Publication for this product

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