概述

  • 产品名称Anti-MTF1抗体
    参阅全部 MTF1 一抗
  • 描述
    小鼠单克隆抗体to MTF1
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant fragment: GTVYDRTTVL IEQDPGTLED EDDDGQCGEH LPFLVGGEEG FHLIDHEAMS QGYVQHIISP DQIHLTINPG STPMPRNIEG ATLTLQSECP ETKRKEVKRY , corresponding to amino acids 41-141 of Human MTF1

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
  • 存储溶液Preservative: None
    PBS, pH 7.2
  • Concentration information loading...
  • 纯度Protein G purified
  • 克隆单克隆
  • 同种型IgG2a
  • 轻链类型kappa
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab55522 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 - 5 µg/ml.

Please see specific references PMID: 22021037 and 18990686 regarding use of this antibody to detect endogenous human MTF1.

靶标

  • 功能Activates the metallothionein I promoter. Binds to the metal responsive element (MRE).
  • 序列相似性Contains 6 C2H2-type zinc fingers.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Metal regulatory transcription factor 1 antibody
    • Metal response element binding transcription factor 1 antibody
    • Metal responsive transcription factor 1 antibody
    • MRE binding transcription factor antibody
    • MRE-binding transcription factor 1 antibody
    • MRE-binding transcription factor antibody
    • MTF 1 antibody
    • MTF1 antibody
    • MTF1_HUMAN antibody
    • Transcription factor MTF-1 antibody
    • Transcription factor MTF1 antibody
    • Zinc regulatory factor antibody
    • ZRF antibody
    see all

Anti-MTF1 antibody 图像

  • Western blot against tagged recombinant protein immunogen using ab55522 MTF1 antibody at 1ug/ml. Predicted band size of the recombinant immunogen is 37 kDa.
    We have only tested this antibody against the reecombinant protein.
    Please see specific references PMID: 22021037 and 18990686 regarding use of this antibody to detect endogenous human MTF1.

Anti-MTF1 antibody (ab55522)参考文献

This product has been referenced in:
  • Liu YC  et al. The Role of Small Ubiquitin-like Modifier-interacting Motif in the Assembly and Regulation of Metal-responsive Transcription Factor 1. J Biol Chem 286:42818-29 (2011). WB ; Human . Read more (PubMed: 22021037) »
  • Bellingham SA  et al. Regulation of prion gene expression by transcription factors SP1 and metal transcription factor-1. J Biol Chem 284:1291-301 (2009). WB ; Human . Read more (PubMed: 18990686) »

See all 2 Publications for this product

Product Wall

Abcam guarantees this product to work in the species/application used in this Abreview.
Application Western blot
Sample Human Cell lysate - whole cell (human MDM)
Loading amount 100 µg
Specification human MDM
Gel Running Conditions Reduced Denaturing (10)
Blocking step BSA as blocking agent for 2 hour(s) and 0 minute(s) · Concentration: 5% · Temperature: RT°C
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提交于 Jan 28 2013

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"