MTEP,mGluR5拮抗剂(ab144307)
Key features and details
- Potent and selective mGluR5 antagonist
- CAS Number: 329205-68-7
- Purity: > 99%
- Soluble in ethanol to 100 mM and in DMSO to 100 mM
- Form / State: Solid
- Source: Synthetic
概述
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产品名称
MTEP,mGluR5拮抗剂 -
描述
Potent and selective mGluR5拮抗剂 -
生物学描述
Potent and selective mGluR5 antagonist. Acts as a negative allosteric modulator at mGluR5. Shows 5-fold more potent anxiolytic effects than MPEP (ab120008). Shows antidepressant and neuroprotective effects in vivo. Orally active. Blood-brain barrier permeable.
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纯度
> 99% -
CAS编号
329205-68-7 -
化学结构
性能
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化学名称
3-[2-(2-Methyl-4-thiazolyl)ethynyl]pyridine -
分子量
200.26 -
分子式
C11H8N2S -
PubChem识别号
9794218 -
存放说明
Store at +4°C. The product can be stored for up to 12 months. -
溶解度概述
Soluble in ethanol to 100 mM and in DMSO to 100 mM -
处理
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour.
Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
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SMILES
CC1=NC(=CS1)C#CC2=CN=CC=C2 -
来源
Synthetic
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研究领域
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
文献 (0)
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