小鼠单克隆抗体[PHL-1] to MTBP
ab34704 recognises MTBP protein.
Human, Chimpanzee 不与反应:
Recombinant amino-terminal HIS6X-tagged polypeptide corresponding to amino acid residues
of human MTBP protein.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Preservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate. pH 7.2
Concentration information loading...
Protein A purified
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000 - 1/20000.
1/200 - 1/2000. Predicted molecular weight: 102 kDa.
Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
Belongs to the MTBP family.
Information by UniProt
MDM 2 binding protein antibody
MDM 2 BP antibody
Western blot - Anti-MTBP antibody [PHL-1] (ab34704)
All lanes :
Anti-MTBP antibody [PHL-1] (ab34704) at 1/500 dilution
Lane 1 :
293 cell lysate with transfection with a full length human expression MTBP construct.
Lane 2 :
293 cell lysate without transfection with a full length human expression MTBP construct.
Developed using the ECL technique.
Predicted band size:
Observed band size:
110 kDa (
why is the actual band size different from the predicted?
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