存放说明 Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
存储溶液 Preservative: 0.01% Sodium Azide
Constituents: 0.15M Sodium chloride, 0.02M Potassium phosphate. pH 7.2
Concentration information loading...
纯度 Protein A purified
Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
1/2000 - 1/20000.
1/200 - 1/2000. Predicted molecular weight: 102 kDa.
功能 Inhibits cell migration in vitro and suppresses the invasive behavior of tumor cells (By similarity). May play a role in MDM2-dependent p53/TP53 homeostasis in unstressed cells. Inhibits autoubiquitination of MDM2, thereby enhancing MDM2 stability. This promotes MDM2-mediated ubiquitination of p53/TP53 and its subsequent degradation.
序列相似性 Belongs to the MTBP family.
Information by UniProt
MDM 2 binding protein antibody
MDM 2 BP antibody
Anti-MTBP antibody [PHL-1] 图像
Western blot - MTBP antibody [PHL-1] (ab34704)
All lanes : Anti-MTBP antibody [PHL-1] (ab34704) at 1/500 dilution Lane 1 : 293 cell lysate with transfection with a full length human expression MTBP construct. Lane 2 : 293 cell lysate without transfection with a full length human expression MTBP construct. developed using the ECL technique Predicted band size : 102 kDa Observed band size : 110 kDa ( why is the actual band size different from the predicted?)
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"