概述

  • 产品名称Anti-MTA1抗体
    参阅全部 MTA1 一抗
  • 描述
    兔多克隆抗体to MTA1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Horse, Cow, Dog, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region within residues 400 and 450 of human MTA1 (SwissProt entry Q13330).

  • 阳性对照
    • Human stomach adenocarcinoma; human lung non small cell carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84136 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/100 - 1/500. Antigen retrieval is not essential but may optimise staining. The use of citrate buffer will enhance staining.

靶标

  • 功能May be involved in the regulation of gene expression by covalent modification of histone proteins. Isoform Long is a corepressor of estrogen receptor (ER). Isoform Short binds to ER and sequesters it in the cytoplasm and enhances non-genomic responses of ER.
  • 组织特异性Widely expressed. High expression in brain, ovaries, adrenal glands and virgin mammary glands. Higher in tumors than in adjacent normal tissue from the same individual.
  • 序列相似性Contains 1 BAH domain.
    Contains 1 ELM2 domain.
    Contains 1 GATA-type zinc finger.
    Contains 1 SANT domain.
  • 发展阶段Highly expressed in metastatic cells.
  • 结构域Isoform Short contains a Leu-Arg-Ile-Leu-Leu motif (ER binding motif).
  • 细胞定位Cytoplasm and Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Metastasis associated 1 antibody
    • Metastasis associated gene 1 antibody
    • Metastasis associated gene 1 protein antibody
    • Metastasis associated protein antibody
    • Metastasis associated protein MTA 1 antibody
    • Metastasis associated protein MTA1 antibody
    • Metastasis-associated protein MTA1 antibody
    • MTA 1 antibody
    • MTA1 antibody
    • MTA1_HUMAN antibody
    see all

Anti-MTA1 antibody 图像

  • ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human stomach adenocarcinoma tissue by Immunohistochemistry. Detection: DAB staining.
  • ab84136, at a 1/100 dilution, staining MTA1 in formalin fixed, paraffin embedded human lung non small cell carcinoma tissue by Immunohistochemistry. Detection: DAB staining.

Anti-MTA1 antibody (ab84136)参考文献

This product has been referenced in:
  • Agboola AO  et al. Clinicopathological and molecular significance of Sumolyation marker (ubiquitin conjugating enzyme 9 (UBC9)) expression in breast cancer of black women. Pathol Res Pract N/A:N/A (2013). IHC-P ; Human . Read more (PubMed: 24176171) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab84136.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"