概述

  • 产品名称Anti-MT3抗体
    参阅全部 MT3 一抗
  • 描述
    小鼠单克隆抗体to MT3
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Recombinant Fragment
    预测可用于: Human, Chimpanzee, Macaque Monkey
  • 免疫原

    GST-tagged recombinant full length protein: MDPETCPCPS GGSCTCADSC KCEGCKCTSC KKSCCSCCPA ECEKCAKDCV, corresponding to amino acids 1-68 of Human MT3

性能

应用

Our Abpromise guarantee covers the use of ab76618 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 7 kDa.
ELISA Use at an assay dependent dilution.

靶标

  • 功能Binds heavy metals. Contains three zinc and three copper atoms per polypeptide chain and only a negligible amount of cadmium. Inhibits survival and neurite formation of cortical neurons in vitro.
  • 组织特异性Abundant in a subset of astrocytes in the normal human brain, but greatly reduced in the Alzheimer disease (AD) brain.
  • 序列相似性Belongs to the metallothionein superfamily. Type 1 family.
  • Information by UniProt
  • 数据库链接
  • 别名
    • GIF antibody
    • GIFB antibody
    • GRIF antibody
    • Growth inhibitory factor antibody
    • Metallothionein 3 (growth inhibitory factor (neurotrophic)) antibody
    • Metallothionein 3 antibody
    • Metallothionein III antibody
    • Metallothionein-3 antibody
    • Metallothionein-III antibody
    • Mt 3 antibody
    • MT III antibody
    • MT-3 antibody
    • MT-III antibody
    • MT3 antibody
    • MT3_HUMAN antibody
    • ZnMT3 antibody
    see all

Anti-MT3 antibody 图像

Anti-MT3 antibody (ab76618)参考文献

This product has been referenced in:
  • Tao YF  et al. Metallothionein III (MT3) is a putative tumor suppressor gene that is frequently inactivated in pediatric acute myeloid leukemia by promoter hypermethylation. J Transl Med 12:182 (2014). WB ; Human . Read more (PubMed: 24962166) »

See 1 Publication for this product

Product Wall

Thank you for contacting us.

The concentration for ab76618 lot GR60074-1 (1171184) is 0.757mg/ml.

I hope this information is helpful to you. Please do not hesitate to contact us if you need any more advice or information.
Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"