概述

  • 产品名称Anti-mSin3A抗体
    参阅全部 mSin3A 一抗
  • 描述
    兔多克隆抗体to mSin3A
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Mouse, Human
    预测可用于: Rat, Horse, Cow, Dog, Chimpanzee, Ferret, Rhesus monkey, Gorilla, Orangutan, Elephant
  • 免疫原

    Synthetic peptide corresponding to a region within residues 1 - 50 of Human mSin3A (NP_056292.1)

  • 阳性对照
    • Human ovarian tumor; Mouse squamous cell carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab84380 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P
  • 应用说明IHC-P: 1/100 - 1/500. Epitope exposure with citrate buffer will enhance staining.
    Note: expected to work on frozen sections.

    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Acts as a transcriptional repressor. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MAD-MAX heterodimers by binding to MAD. The heterodimer then represses transcription by tethering SIN3A to DNA. Acts as a corepressor for REST.
    • 序列相似性Contains 3 PAH (paired amphipathic helix) domains.
    • 翻译后修饰SUMO1 sumoylated by TOPORS. Probably desumoylated by SENP2.
    • 细胞定位Nucleus. Nucleus > nucleolus. Recruited to the nucleolus by SAP30L.
    • Information by UniProt
    • 数据库链接
    • 别名
      • AW553200 antibody
      • DKFZP434K2235 antibody
      • FLJ90319 antibody
      • Histone deacetylase complex subunit Sin 3a antibody
      • Histone deacetylase complex subunit Sin3a antibody
      • KIAA0700 antibody
      • Kiaa4126 antibody
      • mKIAA4126 antibody
      • Paired amphipathic helix protein Sin 3a antibody
      • Paired amphipathic helix protein Sin3a antibody
      • Sin 3a antibody
      • SIN3 homolog A antibody
      • SIN3 homolog A transcription regulator (yeast) antibody
      • SIN3 homolog A transcription regulator antibody
      • SIN3 transcription regulator homolog A antibody
      • Sin3a antibody
      • SIN3A protein antibody
      • SIN3A_HUMAN antibody
      • Transcriptional co repressor Sin 3A antibody
      • Transcriptional co repressor Sin3A antibody
      • Transcriptional corepressor Sin3a antibody
      • Transcriptional regulator SIN3A antibody
      see all

    Anti-mSin3A antibody 图像

    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Mouse squamous cell carcinoma tissue using 1/250 ab84380. Detection: DAB staining.
    • Immunohistochemistry analysis of formalin-fixed, paraffin-embedded Human ovarian tumor tissue using 1/250 ab84380. Detection: DAB staining.

    Anti-mSin3A antibody (ab84380)参考文献

    ab84380 has not yet been referenced specifically in any publications.

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