概述

  • 产品名称Anti-MSI2抗体
    参阅全部 MSI2 一抗
  • 描述
    兔多克隆抗体to MSI2
  • 经测试应用适用于: WB, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Rabbit, Cow, Cat, Dog, Pig, Drosophila melanogaster, Zebrafish
  • 免疫原

    Synthetic peptide corresponding to a region within the N terminal amino acids 2-51 (EANGSQGTSG SANDSQHDPG KMFIGGLSWQ TSPDSLRDYF SKFGEIRECM) of human MSI2 (NP_620412).

  • 阳性对照
    • HepG2 cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab83236 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 35 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay, 1:1562500.

靶标

  • 功能RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
  • 组织特异性Ubiquitous; detected at low levels.
  • 疾病相关Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).
  • 序列相似性Belongs to the Musashi family.
    Contains 2 RRM (RNA recognition motif) domains.
  • 翻译后修饰Phosphorylated.
  • 细胞定位Cytoplasm. Associated with polysomes.
  • Information by UniProt
  • 数据库链接
  • 别名
    • FLJ36569 antibody
    • MGC3245 antibody
    • Msi2 antibody
    • MSI2/HOXA9 fusion gene, included antibody
    • MSI2H antibody
    • MSI2H_HUMAN antibody
    • Musashi 2 antibody
    • Musashi homolog 2 antibody
    • Musashi RNA binding protein 2 antibody
    • Musashi, Drosophila, homolog of, 2 antibody
    • Musashi-2 antibody
    • RNA binding protein Musashi homolog 2 antibody
    • RNA-binding protein Musashi homolog 2 antibody
    • WD 40 repeat protein MSI2 antibody
    see all

Anti-MSI2 antibody 图像

  • Anti-MSI2 antibody (ab83236) at 1 µg/ml + HepG2 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 35 kDa
    Observed band size : 35 kDa

Anti-MSI2 antibody (ab83236)参考文献

This product has been referenced in:
  • Cox JL  et al. The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells. PLoS One 8:e62857 (2013). WB ; Human . Read more (PubMed: 23667531) »

See 1 Publication for this product

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