概述

  • 产品名称
  • 描述
    兔多克隆抗体to MSI2
  • 经测试应用
    适用于: IPmore details
    不适用于: WB
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Guinea pig, Ferret, Lizard, Rhesus monkey, Gorilla, Orangutan
  • 免疫原

    Synthetic peptide, corresponding to a region between amino acids 250-300 of Human MSI2 (NP_620412.1).

  • 阳性对照
    • HeLa whole cell lysate.

性能

应用

Our Abpromise guarantee covers the use of ab114107 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IP Use at 2-10 µg/mg of lysate.
  • 应用说明
    Is unsuitable for WB.
  • 靶标

    • 功能
      RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system.
    • 组织特异性
      Ubiquitous; detected at low levels.
    • 疾病相关
      Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23).
    • 序列相似性
      Belongs to the Musashi family.
      Contains 2 RRM (RNA recognition motif) domains.
    • 翻译后修饰
      Phosphorylated.
    • 细胞定位
      Cytoplasm. Associated with polysomes.
    • Information by UniProt
    • 数据库链接
    • 别名
      • FLJ36569 antibody
      • MGC3245 antibody
      • Msi2 antibody
      • MSI2/HOXA9 fusion gene, included antibody
      • MSI2H antibody
      • MSI2H_HUMAN antibody
      • Musashi 2 antibody
      • Musashi homolog 2 antibody
      • Musashi RNA binding protein 2 antibody
      • Musashi, Drosophila, homolog of, 2 antibody
      • Musashi-2 antibody
      • RNA binding protein Musashi homolog 2 antibody
      • RNA-binding protein Musashi homolog 2 antibody
      • WD 40 repeat protein MSI2 antibody
      see all

    图片

    • Detection of Human MSI2 by Western blot of Immunoprecipitate.
      MSI2 was immunoprecipitated from HeLa whole cell lysate, using ab114107 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114107 was used for the subsequent WB at 1 µg/ml.
      Detection: Chemiluminescence with an exposure time of 30 seconds.

    文献

    ab114107 has not yet been referenced specifically in any publications.

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