Anti-MSI2抗体(ab114107)
Key features and details
- Rabbit polyclonal to MSI2
- Suitable for: IP
- Reacts with: Human
- Isotype: IgG
选择批间可重复性更高的重组抗体
- 研究可靠 —— 各批次间结果一致且可重复
- 长期批量供应 —— 采用重组技术,可实现快速生产
- 首次实验即可成功 —— 经过大量验证确认了特异性
- 符合伦理标准 —— 产品不含动物成分
概述
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产品名称
Anti-MSI2抗体
参阅全部 MSI2 一抗 -
描述
兔多克隆抗体to MSI2 -
宿主
Rabbit -
经测试应用
适用于: IPmore details -
种属反应性
与反应: Human
预测可用于: Mouse, Guinea pig, Ferret, Lizard, Rhesus monkey, Gorilla, Orangutan -
免疫原
Synthetic peptide, corresponding to a region between amino acids 250-300 of Human MSI2 (NP_620412.1).
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阳性对照
- HeLa whole cell lysate (ab150035).
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
pH: 7
Preservative: 0.09% Sodium azide
Constituent: 99% Tris citrate/phosphate
pH 7 to 8 -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
ab114107 was affinity purified using an epitope specific to MSI2 immobilized on solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Positive Controls
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab114107于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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IP |
Use at 2-10 µg/mg of lysate.
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说明 |
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IP
Use at 2-10 µg/mg of lysate. |
靶标
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功能
RNA binding protein that regulates the expression of target mRNAs at the translation level. May play a role in the proliferation and maintenance of stem cells in the central nervous system. -
组织特异性
Ubiquitous; detected at low levels. -
疾病相关
Note=Chromosomal aberrations involving MSI2 may contribute to disease progression in chronic myeloid leukemia. Translocation t(7;17)(p15;q23) with HOXA9; translocation t(7;17)(q32-34;q23). -
序列相似性
Belongs to the Musashi family.
Contains 2 RRM (RNA recognition motif) domains. -
翻译后修饰
Phosphorylated. -
细胞定位
Cytoplasm. Associated with polysomes. - Information by UniProt
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数据库链接
- Entrez Gene: 124540 Human
- Entrez Gene: 76626 Mouse
- Omim: 607897 Human
- SwissProt: Q96DH6 Human
- SwissProt: Q920Q6 Mouse
- Unigene: 658922 Human
- Unigene: 400451 Mouse
- Unigene: 428433 Mouse
see all -
别名
- FLJ36569 antibody
- MGC3245 antibody
- Msi2 antibody
see all
图片
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Detection of Human MSI2 by Western blot of Immunoprecipitate.
MSI2 was immunoprecipitated from HeLa whole cell lysate, using ab114107 at 6 µg/mg lysate (1 mg for IP, 20% of IP loaded). ab114107 was used for the subsequent WB at 1 µg/ml.
Detection: Chemiluminescence with an exposure time of 30 seconds.
数据表及文件
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SDS download
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Datasheet download
文献 (1)
ab114107 被引用在 1 文献中.
- Cragle CE et al. Musashi interaction with poly(A)-binding protein is required for activation of target mRNA translation. J Biol Chem 294:10969-10986 (2019). PubMed: 31152063