概述

  • 产品名称Anti-MRP3抗体
    参阅全部 MRP3 一抗
  • 描述
    兔多克隆抗体to MRP3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Pig
  • 免疫原

    Synthetic peptide corresponding to a region within internal amino acids 684-733 (KVHMKGSVAY VPQQAWIQNC TLQENVLFGK ALNPKRYQQT LEACALLADL) of Human MRP3 (NP_003777).

  • 阳性对照
    • MCF7 cell lysate.

性能

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应用

Our Abpromise guarantee covers the use of ab84887 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 1 µg/ml. Predicted molecular weight: 169 kDa. Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.

靶标

  • 功能May act as an inducible transporter in the biliary and intestinal excretion of organic anions. Acts as an alternative route for the export of bile acids and glucuronides from cholestatic hepatocytes.
  • 组织特异性Mainly expressed in the liver. Also expressed in small intestine, colon, prostate, testis, brain and at a lower level in the kidney.
  • 序列相似性Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily.
    Contains 2 ABC transmembrane type-1 domains.
    Contains 2 ABC transporter domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • ABC 31 antibody
    • ABC31 antibody
    • ABCC 3 antibody
    • ABCC3 antibody
    • ATP binding cassette sub family C (CFTR/MRP) member 3 antibody
    • ATP binding cassette sub family C member 3 antibody
    • ATP-binding cassette sub-family C member 3 antibody
    • Canalicular multispecific organic anion transporter 2 antibody
    • Canicular multispecific organic anion transporter antibody
    • CMOAT 2 antibody
    • CMOAT2 antibody
    • EST90757 antibody
    • MLP 2 antibody
    • MLP2 antibody
    • MOAT D antibody
    • MOAT-D antibody
    • MOATD antibody
    • MRP 3 antibody
    • MRP3_HUMAN antibody
    • Multi specific organic anion transporter D antibody
    • Multi-specific organic anion transporter D antibody
    • Multidrug resistance associated protein 3 antibody
    • Multidrug resistance associated protein antibody
    • Multidrug resistance-associated protein 3 antibody
    • Multispecific organic anion tranporter D antibody
    see all

Anti-MRP3 antibody 图像

  • Anti-MRP3 antibody (ab84887) at 1 µg/ml (in 5% skim milk / PBS buffer) + MCF7 cell lysate at 10 µg

    Secondary
    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 169 kDa
    Observed band size : 155 kDa (why is the actual band size different from the predicted?)
    Additional bands at : <40 kDa. We are unsure as to the identity of these extra bands.

Anti-MRP3 antibody (ab84887)参考文献

ab84887 has not yet been referenced specifically in any publications.

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