概述

  • 产品名称Anti-MRGX1抗体
  • 描述
    兔多克隆抗体to MRGX1
  • 经测试应用适用于: WB, ELISA, ICC/IFmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide derived from internal sequence of human GPCR MRGX1.

  • 阳性对照
    • Extracts from MCF-7 cells. HepG2 cells.

性能

  • 形式Liquid
  • 存放说明Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C.
  • 存储溶液Preservative: 0.02% Sodium Azide
    Constituents: 50% Glycerol, PBS (without Mg2+ and Ca2+), 150mM Sodium chloride, pH 7.4
  • Concentration information loading...
  • 纯度Immunogen affinity purified
  • 克隆多克隆
  • 同种型IgG
  • 研究领域

应用

Our Abpromise guarantee covers the use of ab77519 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/1000. Predicted molecular weight: 36 kDa.
ELISA 1/5000.
ICC/IF 1/500 - 1/1000.

靶标

  • 相关性MRGX1 is an opiod receptor that has been reported exclusively in dorsal root ganglion. MRGX1 is probably involved in the function of nociceptive neurons and may regulate nociceptor function and/or development, including the sensation or modulation of pain. It is potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells.
  • 细胞定位Cell Membrane; Multi-pass membrane protein.
  • 数据库链接
  • 别名
    • GPCR antibody
    • MAS related gene MRGX1 antibody
    • MAS related GPR member X1 antibody
    • MRGPRX1 antibody
    • MRGX1 antibody
    • SNSR4 antibody
    see all

Anti-MRGX1 antibody 图像

  • All lanes : Anti-MRGX1 antibody (ab77519) at 1/500 dilution

    Lane 1 : Extracts from MCF-7 cells
    Lane 2 : Extracts from MCF-7 cells with immunising peptide at 5 µg

    Lysates/proteins at 5 µg per lane.


    Predicted band size : 36 kDa
    Observed band size : 36 kDa
  • Immunofluorescence analysis of GPCR MRGX1 in HepG2 cells using ab77519, at 1/500 dilution, in the absence or presence of immunising peptide

Anti-MRGX1 antibody (ab77519)参考文献

ab77519 has not yet been referenced specifically in any publications.

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