Anti-MRGX1抗体(ab77519)
Key features and details
- Rabbit polyclonal to MRGX1
- Suitable for: WB, ICC/IF
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-MRGX1抗体 -
描述
兔多克隆抗体to MRGX1 -
宿主
Rabbit -
经测试应用
适用于: WB, ICC/IFmore details -
种属反应性
与反应: Human -
免疫原
Synthetic peptide derived from internal sequence of human GPCR MRGX1.
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阳性对照
- Extracts from MCF-7 cells. HepG2 cells.
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Store at -20°C. Stable for 12 months at -20°C. -
存储溶液
pH: 7.40
Preservative: 0.02% Sodium azide
Constituents: 50% Glycerol, 0.87% Sodium chloride, PBS
Without Mg2+ and Ca2+ -
Concentration information loading...
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纯度
Immunogen affinity purified -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab77519于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/500 - 1/1000. Predicted molecular weight: 36 kDa.
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ICC/IF |
1/500 - 1/1000.
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说明 |
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WB
1/500 - 1/1000. Predicted molecular weight: 36 kDa. |
ICC/IF
1/500 - 1/1000. |
靶标
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功能
Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22)(PubMed:26582731). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner. -
组织特异性
Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons. -
序列相似性
Belongs to the G-protein coupled receptor 1 family. Mas subfamily. -
细胞定位
Cell membrane. - Information by UniProt
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数据库链接
- Entrez Gene: 259249 Human
- Omim: 607227 Human
- SwissProt: Q96LB2 Human
- Unigene: 711459 Human
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别名
- GPCR antibody
- MAS related gene MRGX1 antibody
- MAS related GPR member X1 antibody
see all
图片
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All lanes : Anti-MRGX1 antibody (ab77519) at 1/500 dilution
Lane 1 : Extracts from MCF-7 cells
Lane 2 : Extracts from MCF-7 cells with immunising peptide at 5 µg
Lysates/proteins at 5 µg per lane.
Predicted band size: 36 kDa
Observed band size: 36 kDa -
Immunofluorescence analysis of GPCR MRGX1 in HepG2 cells using ab77519, at 1/500 dilution, in the absence or presence of immunising peptide
实验方案
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab77519 尚未被引用在任何文献中。