Anti-MRG15抗体(ab106818)

概述

  • 产品名称Anti-MRG15抗体
    参阅全部 MRG15 一抗
  • 描述
    山羊多克隆抗体to MRG15
  • 特异性 This antibody is expected to recognise both reported isoforms.
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human, Pig
    预测可用于: Cow
  • 免疫原

    Synthetic peptide:

    APKQDPKPKFQEG-C

    , corresponding to N terminal amino acids 2-14 of Human MRG15 (NP_006782.1; NP_996670.1.)

  • 阳性对照
    • Human Liver lysates
  • 常规说明

    This product will identify isoform 1 and isoform 2.

性能

应用

Our Abpromise guarantee covers the use of ab106818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Predicted molecular weight: 41 kDa.
IHC-P Use a concentration of 2 - 4 µg/ml.
ELISA Use at an assay dependent concentration.

Antibody detection limit dilution 1:128000

靶标

  • 功能Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the mSin3A complex which acts to repress transcription by deacetylation of nucleosomal histones. Required for homologous recombination repair (HRR) and resistance to mitomycin C (MMC). Involved in the localization of PALB2, BRCA2 and RAD51, but not BRCA1, to DNA-damage foci.
  • 序列相似性Belongs to the MRG family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CG6363 antibody
    • Eaf3 antibody
    • Esa1p associated factor 3 homolog antibody
    • FWP006 antibody
    • HsT17725 antibody
    • MEAF3 antibody
    • MO4L1_HUMAN antibody
    • MORF related gene on chromosome 15 antibody
    • MORF-related gene 15 protein antibody
    • Morf4l1 antibody
    • MORFRG15 antibody
    • Mortality factor 4 like 1 antibody
    • Mortality factor 4 like protein 1 antibody
    • Mortality factor 4-like protein 1 antibody
    • MRG15 antibody
    • Protein MSL3-1 antibody
    • S863-6 antibody
    • Transcription factor-like protein MRG15 antibody
    see all

Anti-MRG15 antibody 图像

  • All lanes : Anti-MRG15 antibody (ab106818) at 0.3 µg/ml

    Lane 1 : Mouse liver tissue lysate (in RIPA buffer)
    Lane 2 : Rat liver tissue lysate (in RIPA buffer)
    Lane 3 : Pig liver tissue lysate (in RIPA buffer)

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 41 kDa
    Additional bands at : 37 kDa. We are unsure as to the identity of these extra bands.

    Goat Anti-MRG15 / MORF4L1 Antibody (EB06079) - Everest Biotech Ltd

    Primary incubation was 1 hour. Detected by chemiluminescence.

     

  • Lane 1 :
    Lane 2 :

    Lane 1 : NIH3T3 cell lysate (in RIPA buffer)
    Lane 2 : HepG2 cell lysate (in RIPA buffer)

    Lysates/proteins at 35 µg per lane.


    Predicted band size : 41 kDa
    Additional bands at : 37 kDa. We are unsure as to the identity of these extra bands.

    Primary incubation was 1 hour. Detected by chemiluminescence.

     

     

  • Anti-MRG15 antibody (ab106818) at 0.1 µg/ml + Mouse Liver Lysate in RIPA buffer at 35 µg

    Predicted band size : 41 kDa
    Primary incubation 1 hour.

Anti-MRG15 antibody (ab106818)参考文献

ab106818 has not yet been referenced specifically in any publications.

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