RabMAb

Anti-MRCL3抗体[EP1456Y] (ab81273)

概述

  • 产品名称Anti-MRCL3抗体[EP1456Y]
    参阅全部 MRCL3 一抗
  • 描述
    兔单克隆抗体[EP1456Y] to MRCL3
  • 经测试应用适用于: WB, ICC, Flow Cytmore details
    不适用于: IHC-P or IP
  • 种属反应性
    与反应: Human
  • 免疫原

    A synthetic peptide corresponding to residues near the N terminus of human MRCL3

  • 阳性对照
    • 293T cell lysate
  • 常规说明

    Produced using Abcam’s RabMAb® technology. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,487.

    Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information.

性能

应用

Our Abpromise guarantee covers the use of ab81273 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/500 - 1/2000. Predicted molecular weight: 20 kDa.
ICC 1/250.
Flow Cyt 1/20.

ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

  • 应用说明Is unsuitable for IHC-P or IP.
  • 靶标

    • 功能Myosin regulatory subunit that plays an important role in regulation of both smooth muscle and nonmuscle cell contractile activity via its phosphorylation. Implicated in cytokinesis, receptor capping, and cell locomotion.
    • 序列相似性Contains 3 EF-hand domains.
    • 翻译后修饰Phosphorylation increases the actin-activated myosin ATPase activity and thereby regulates the contractile activity. It is required to generate the driving force in the migration of the cells but not necessary for localization of myosin-2 at the leading edge.
    • Information by UniProt
    • 数据库链接
    • 别名
      • ML12A_HUMAN antibody
      • MLC 2B antibody
      • MLC-2B antibody
      • MLCB antibody
      • MYL12A antibody
      • Myosin regulatory light chain 12A antibody
      • Myosin regulatory light chain 2 antibody
      • Myosin regulatory light chain 2, nonsarcomeric antibody
      • Myosin regulatory light chain MRCL3 antibody
      • Myosin regulatory light chain MRLC3 antibody
      • Myosin RLC antibody
      • Myosin, light polypeptide, regulatory, non sarcomeric (20kD) antibody
      • nonsarcomeric antibody
      • RLC antibody
      see all

    Anti-MRCL3 antibody [EP1456Y] 图像

    • Anti-MRCL3 antibody [EP1456Y] (ab81273) at 1/1000 dilution + 293T cell lysate at 10 µg

      Secondary
      Goat anti-rabbit HRP labelled IgG at 1/2000 dilution

      Predicted band size : 20 kDa
      Observed band size : 20 kDa

    Anti-MRCL3 antibody [EP1456Y] (ab81273)参考文献

    ab81273 has not yet been referenced specifically in any publications.

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    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"