Anti-TTK/Mps1抗体(ab24226)
Key features and details
- Rabbit polyclonal to TTK/Mps1
- Suitable for: WB
- Reacts with: Human
- Isotype: IgG
概述
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产品名称
Anti-TTK/Mps1抗体
参阅全部 TTK/Mps1 一抗 -
描述
兔多克隆抗体to TTK/Mps1 -
宿主
Rabbit -
特异性
ab24226 reacts with TTK (Msp1) protein. -
经测试应用
适用于: WBmore details -
种属反应性
与反应: Human
预测可用于: Rabbit, Horse, Guinea pig, Cow, Dog, Chimpanzee, Ferret, Cynomolgus monkey, Rhesus monkey, Orangutan, Bat -
免疫原
Synthetic peptide corresponding to Human TTK/Mps1 aa 700-750.
Sequence:DVWSLGCILYYMTYGKTPFQQIINQISKLHAIIDPNHEIEFPDIPEKDLQ D
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常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
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形式
Liquid -
存放说明
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. -
存储溶液
Preservative: 0.09% Sodium azide
Constituents: 0.021% PBS, 1.764% Sodium citrate, 1.815% Tris -
Concentration information loading...
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纯度
Immunogen affinity purified -
纯化说明
Antibody was affinity purified using an epitope specific to TTK immobilized on solid support. -
克隆
多克隆 -
同种型
IgG -
研究领域
相关产品
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Compatible Secondaries
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Isotype control
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Recombinant Protein
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab24226于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
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WB |
1/2500 - 1/25000. Detects a band of approximately 95 kDa (predicted molecular weight: 95 kDa).
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说明 |
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WB
1/2500 - 1/25000. Detects a band of approximately 95 kDa (predicted molecular weight: 95 kDa). |
靶标
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功能
Phosphorylates proteins on serine, threonine, and tyrosine. Probably associated with cell proliferation. Essential for chromosome alignment by enhancing AURKB activity (via direct CDCA8 phosphorylation) at the centromere, and for the mitotic checkpoint. -
组织特异性
Present in rapidly proliferating cell lines. -
序列相似性
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.
Contains 1 protein kinase domain. - Information by UniProt
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数据库链接
- Entrez Gene: 7272 Human
- Omim: 604092 Human
- SwissProt: Q4R945 Cynomolgus monkey
- SwissProt: P33981 Human
- Unigene: 169840 Human
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别名
- cancer/testis antigen 96 antibody
- CT96 antibody
- Dual specificity protein kinase TTK antibody
see all
图片
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Detection of Human TTK/Mps1 by Western Blot and Immunoprecipitation.
Samples: Whole cell lysate (15 and 50 µg for A; 50 µg for B; 2 mg for B) from HeLa cells. In B, HeLa cells were treated with an siRNA for vimentin (control) or TTK/Mps1 Ab24226 used at 0.033 (A) and 0.33 (B) µg/ml for WB and at 1 µg/2 mg lysate for IP (C). TTK/Mps1 was also immunoprecipitated with Ab24226 using 1 µg/2 mg lysate. IP reactions were controlled using normal rabbit IgG (control IP). Immunoprecipitated TTK/Mps1 was blotted using a goat antibody directed to an upstream epitope on TTK/Mps1. Detection: Chemiluminescence with exposure times of 1 minute (A), 15 seconds (B) and 30 seconds (C).
数据表及文件
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SDS download
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Datasheet download
文献 (0)
ab24226 尚未被引用在任何文献中。