Anti-MPRIP抗体(ab111381)

概述

  • 产品名称Anti-MPRIP抗体
    参阅全部 MPRIP 一抗
  • 描述
    兔多克隆抗体to MPRIP
  • 特异性ab111381 detects endogenous levels of total MPRIP protein.
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from an internal region of Human MPRIP.

  • 阳性对照
    • Human lymph node tissue.

性能

应用

Our Abpromise guarantee covers the use of ab111381 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.
  • 序列相似性Contains 2 PH domains.
  • 细胞定位Cytoplasm > cytoskeleton. Colocalizes with F-actin.
  • Information by UniProt
  • 数据库链接
  • 别名
    • 9530046C02 antibody
    • AA536749 antibody
    • AI647711 antibody
    • C76423 antibody
    • KIAA0864 antibody
    • M-RIP antibody
    • MGC67316 antibody
    • mKIAA0864 antibody
    • Mprip antibody
    • MPRIP_HUMAN antibody
    • Myosin phosphatase Rho-interacting protein antibody
    • p116 Rho-interacting protein antibody
    • p116Rip antibody
    • Rho-interacting protein 3 antibody
    • Rhoip3 antibody
    • RIP3 antibody
    • RP23-180B18.4 antibody
    see all

Anti-MPRIP antibody 图像

  • ab111381 at 1/50 dilution staining MPRIP in paraffin-embedded Human Lymph tissue by Immunohistochemistry. The image on the right is treated with the synthesized peptide.

Anti-MPRIP antibody (ab111381)参考文献

ab111381 has not yet been referenced specifically in any publications.

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