概述

  • 产品名称Anti-MPDU1抗体
  • 描述
    兔多克隆抗体to MPDU1
  • 经测试应用适用于: WB, ELISA, IHC-Pmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide (10-30 aa in length) in the region of 259~272 of MPDU1(Human) conjugated to KLH

  • 阳性对照
    • Human breast carcinoma.

性能

应用

Our Abpromise guarantee covers the use of ab38856 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500.
ELISA 1/1000.
IHC-P Use at an assay dependent concentration.

靶标

  • 功能Required for normal utilization of mannose-dolichol phosphate (Dol-P-Man) in the synthesis of N-linked and O-linked oligosaccharides and GPI anchors.
  • 疾病相关Defects in MPDU1 are the cause of congenital disorder of glycosylation type 1F (CDG1F) [MIM:609180]. CDGs are a family of severe inherited diseases caused by a defect in protein N-glycosylation. They are characterized by under-glycosylated serum proteins. These multisystem disorders present with a wide variety of clinical features, such as disorders of the nervous system development, psychomotor retardation, dysmorphic features, hypotonia, coagulation disorders, and immunodeficiency. The broad spectrum of features reflects the critical role of N-glycoproteins during embryonic development, differentiation, and maintenance of cell functions.
  • 序列相似性Belongs to the MPDU1 (TC 2.A.43.3) family.
    Contains 2 PQ-loop domains.
  • 细胞定位Membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • CDGIF antibody
    • LEC35 antibody
    • mannose P dolichol utilization defect 1 antibody
    • Mannose-P-dolichol utilization defect 1 protein antibody
    • MPDU1 antibody
    • MPU1_HUMAN antibody
    • PQLC5 antibody
    • SL15 antibody
    • Suppressor of Lec15 and Lec35 glycosylation mutation homolog antibody
    see all

Anti-MPDU1 antibody 图像

  • Ab38856 at 1/50 dilution staining human breast carcinoma; a peroxidase-conjugated secondary antibody, followed by AEC staining was used.
  • Anti-MPDU1 antibody (ab38856)ab38856 used at a dilution of 1:100 - 1:500

Anti-MPDU1 antibody (ab38856)参考文献

ab38856 has not yet been referenced specifically in any publications.

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