小鼠UCP3肽(ab4994)

概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • AccessionP56501
    • 种属Mouse
    • 序列RALMKVQVLRESPF
    • 氨基酸295 to 308

相关产品

技术指标

Our Abpromise guarantee covers the use of ab4994 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • 补充说明


    This peptide may be used for neutralization and control experiments with the polyclonal antibody that reacts with this product and mouse UCP 3, catalog ab3477. Using a solution of peptide of equal volume and concentration to the corresponding antibody will yield a large molar excess of peptide (~ 70-fold) for competitive inhibition of antibody-protein binding reactions.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

常规信息

  • 别名
    • Mitochondrial uncoupling protein 3
    • SLC25A9
    • Solute carrier family 25 member 9
    • UCP 3
    • UCP3
    • UCP3_HUMAN
    • Uncoupling protein 3
    • Uncoupling protein 3 mitochondrial proton carrier
    see all
  • 功能UCP are mitochondrial transporter proteins that create proton leaks across the inner mitochondrial membrane, thus uncoupling oxidative phosphorylation. As a result, energy is dissipated in the form of heat. May play a role in the modulation of tissue respiratory control. Participates in thermogenesis and energy balance.
  • 组织特异性Only in skeletal muscle and heart. Is more expressed in glycolytic than in oxidative skeletal muscles.
  • 疾病相关Defects in UCP3 may be involved in obesity (OBESITY) [MIM:601665]. It is a condition characterized by an increase of body weight beyond the limitation of skeletal and physical requirements, as the result of excessive accumulation of body fat.
  • 序列相似性Belongs to the mitochondrial carrier family.
    Contains 3 Solcar repeats.
  • 细胞定位Mitochondrion inner membrane.
  • Information by UniProt

Mouse UCP3 peptide (ab4994)参考文献

ab4994 has not yet been referenced specifically in any publications.

Product Wall

Thank you for your enquiry. Here is the protocol: BLOCKING WITH IMMUNIZING PEPTIDE (BL) PROTOCOL It is not uncommon to see more than one band in Western blotting when probing with a given antibody or to see more diffuse staining in immunolocali...

Read More

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"