概述

描述

  • 性质Synthetic
  • 氨基酸序列
    • 种属Mouse

相关产品

技术指标

Our Abpromise guarantee covers the use of ab39849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-SIGIRR antibody (ab25875)

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: 0.02% Sodium Azide
    Constituents: 0.1% BSA, PBS, pH 7.2

常规信息

  • 别名
    • Ig IL1 related receptor
    • MGC110992
    • SIGIR_HUMAN
    • SIGIRR
    • Single Ig IL 1 related receptor
    • Single Ig IL-1-related receptor
    • Single Ig IL-1R-related molecule
    • Single Ig IL1R Related Molecule
    • Single immunoglobulin and toll interleukin 1 receptor (TIR) domain
    • Single immunoglobulin and toll interleukin 1 receptor domain
    • Single immunoglobulin domain containing IL1R related protein
    • Single immunoglobulin domain IL1R1 related
    • Single immunoglobulin domain-containing IL1R-related protein
    • TIR 8
    • TIR8
    • Toll/interleukin 1 receptor 8
    • Toll/interleukin-1 receptor 8
    see all
  • 功能Acts as a negative regulator of the Toll-like and IL-1R receptor signaling pathways. Attenuates the recruitment of receptor-proximal signaling components to the TLR4 receptor, probably through an TIR-TIR domain interaction with TLR4. Through its extracellular domain interferes with the heterodimerization of Il1R1 and IL1RAP.
  • 组织特异性Mainly expressed in epithelial tissues such as kidney, lung and gut.
  • 序列相似性Belongs to the interleukin-1 receptor family.
    Contains 1 Ig-like C2-type (immunoglobulin-like) domain.
    Contains 1 TIR domain.
  • 细胞定位Membrane.
  • Information by UniProt

Mouse SIGIRR peptide (ab39849)参考文献

ab39849 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab39849.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"