序列 This sequence is highly conserved in rat paxillin and is also found in all three isoforms, alpha, beta and gamma. There is low homology between this sequence and the conserved sequence site in human paxillin (around Serine 85).
修饰 phospho S83 技术指标
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Blocking - Blocking peptide for Anti-Paxillin (phospho S83) antibody (
Concentration information loading... 制备和贮存
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Preservative: 0.05% Sodium Azide
Paired box protein Pax 1
功能 Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).
序列相似性 Belongs to the paxillin family. Contains 4 LIM zinc-binding domains.
翻译后修饰 Phosphorylated on tyrosine residues during integrin-mediated cell adhesion, embryonic development, fibroblast transformation and following stimulation of cells by mitogens.
细胞定位 Cytoplasm > cytoskeleton. Cell junction > focal adhesion.
Information by UniProt
Mouse Paxillin (phospho S83) peptide (ab42724)参考文献
has not yet been referenced specifically in any publications.
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