概述

描述

  • 性质Synthetic

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技术指标

Our Abpromise guarantee covers the use of ab34093 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 形式Liquid
  • 补充说明

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • Cell surface retention sequence-binding protein 1
    • CRSBP 1
    • CRSBP-1
    • CRSBP1
    • extracellular link domain containing 1
    • extracellular link domain-containing 1
    • Extracellular link domain-containing protein 1
    • HAR
    • Hyaluronic acid receptor
    • Lymphatic endothelium specific hyaluronan receptor
    • lymphatic vessel endothelial hyaluronan receptor 1
    • Lymphatic vessel endothelial hyaluronic acid receptor 1
    • LYVE 1
    • LYVE-1
    • LYVE1
    • LYVE1_HUMAN
    • XLKD1
    see all
  • 功能Ligand-specific transporter trafficking between intracellular organelles (TGN) and the plasma membrane. Plays a role in autocrine regulation of cell growth mediated by growth regulators containing cell surface retention sequence binding (CRS). May act as a hyaluronan (HA) transporter, either mediating its uptake for catabolism within lymphatic endothelial cells themselves, or its transport into the lumen of afferent lymphatic vessels for subsequent re-uptake and degradation in lymph nodes.
  • 组织特异性Mainly expressed in endothelial cells lining lymphatic vessels.
  • 序列相似性Contains 1 Link domain.
  • 翻译后修饰O-glycosylated.
  • 细胞定位Membrane. Localized to the plasma membrane and in vesicles near extranuclear membranes which may represent trans-Golgi network (TGN) and endosomes/prelysosomeal compartments. Undergoes ligand-dependent internalization and recycling at the cell surface.
  • Information by UniProt

Mouse LYVE1 peptide (ab34093)参考文献

ab34093 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"