小鼠Glutamine Synthetase肽(ab73592)

概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • Accession
    • 种属
      Mouse

技术指标

Our Abpromise guarantee covers the use of ab73592 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 纯度
    70 - 90% by HPLC.

  • 形式
    Liquid
  • 补充说明

     

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • cell proliferation-inducing protein 59
    • GLNA
    • GLNA_HUMAN
    • GLNS
    • GLUL
    • Glutamate ammonia ligase
    • Glutamate decarboxylase
    • Glutamate--ammonia ligase
    • glutamine synthase
    • Glutamine synthetase
    • GS
    • PIG 43
    • PIG 59
    • PIG43
    • PIG59
    • Proliferation inducing protein 43
    see all
  • 功能
    This enzyme has 2 functions: it catalyzes the production of glutamine and 4-aminobutanoate (gamma-aminobutyric acid, GABA), the latter in a pyridoxal phosphate-independent manner (By similarity). Essential for proliferation of fetal skin fibroblasts.
  • 疾病相关
    Defects in GLUL are the cause of congenital systemic glutamine deficiency (CSGD) [MIM:610015]. CSGD is a rare developmental disorder with severe brain malformation resulting in multi-organ failure and neonatal death. Glutamine is largely absent from affected patients serum, urine and cerebrospinal fluid.
  • 序列相似性
    Belongs to the glutamine synthetase family.
  • 发展阶段
    Expressed during early fetal stages.
  • 细胞定位
    Cytoplasm. Mitochondrion.
  • Information by UniProt

文献

ab73592 has not yet been referenced specifically in any publications.

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