概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • Accession
    • 种属
      Mouse
    • 序列
      GTHSLTKFSCKNA
    • 氨基酸
      128 to 140

技术指标

Our Abpromise guarantee covers the use of ab22916 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

常规信息

  • 别名
    • AD 8
    • AD8
    • Amyloid angiopathy and cerebral hemorrhage
    • ARMD11
    • bA218C14.4
    • bA218C14.4 (cystatin C)
    • Cst 3
    • Cst3
    • CST3 protein
    • Cystatin 3
    • Cystatin-3
    • Cystatin-C
    • Cystatin3
    • CystatinC
    • CYTC_HUMAN
    • Epididymis secretory protein Li 2
    • Gamma trace
    • Gamma-trace
    • HCCAA
    • HEL S 2
    • MGC117328
    • Neuroendocrine basic polypeptide
    • Post gamma globulin
    • Post-gamma-globulin
    see all
  • 功能
    As an inhibitor of cysteine proteinases, this protein is thought to serve an important physiological role as a local regulator of this enzyme activity.
  • 组织特异性
    Expressed in submandibular and sublingual saliva but not in parotid saliva (at protein level). Expressed in various body fluids, such as the cerebrospinal fluid and plasma. Expressed in highest levels in the epididymis, vas deferens, brain, thymus, and ovary and the lowest in the submandibular gland.
  • 疾病相关
    Amyloidosis 6
    Macular degeneration, age-related, 11
  • 序列相似性
    Belongs to the cystatin family.
  • 翻译后修饰
    The Thr-25 variant is O-glycosylated with a core 1 or possibly core 8 glycan. The signal peptide of the O-glycosylated Thr-25 variant is cleaved between Ala-20 and Val-21.
  • 细胞定位
    Secreted.
  • Information by UniProt

文献

ab22916 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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