概述

  • 产品名称小鼠CDKN2A/p19ARF肽

描述

  • 性质Synthetic
  • 来源CHO cells

技术指标

Our Abpromise guarantee covers the use of ab2659 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking

  • 形式Liquid
  • 补充说明This product is primarily designed for use as a blocking peptide for ab80, Rabbit polyclonal to mouse p19ARF.

    - First try to dissolve a small amount of peptide in either water or buffer. The more charged residues on a peptide, the more soluble it is in aqueous solutions.
    - If the peptide doesn’t dissolve try an organic solvent e.g. DMSO, then dilute using water or buffer.
    - Consider that any solvent used must be compatible with your assay. If a peptide does not dissolve and you need to recover it, lyophilise to remove the solvent.
    - Gentle warming and sonication can effectively aid peptide solubilisation. If the solution is cloudy or has gelled the peptide may be in suspension rather than solubilised.
    - Peptides containing cysteine are easily oxidised, so should be prepared in solution just prior to use.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Information available upon request.

常规信息

  • 别名
    • ARF
    • CDKN2A
    • Cyclin dependent kinase inhibitor 2A
    • INK4
    • MTS1
    • P19
    see all
  • 相关性The gene for CDK2NA generates several transcripts/proteins which differ from each other in their first exons. Three of these transcripts are generated by alternative splicing (isoform 1 a.k.a p16INK4A, isoform 2 and isoform 3 a.k.a p12), two of which are known to function as inhibitors of CDK4 kinase. One other transcript that is generated from this gene contains an alternate reading frame (ARF), with the first exon located 20kb upstream of the remainder of the gene(isoform 4 a.k.a. p14ARF, p19ARF, ARF). In spite of the structural and some functional differences, all the proteins encoded by the CDKN2A gene are involved in cell cycle G1 control.
  • 细胞定位Nuclear

Mouse CDKN2A/p19ARF peptide (ab2659)参考文献

This product has been referenced in:
  • Chidlow G  et al. Ocular Expression and Distribution of Products of the POAG-Associated Chromosome 9p21 Gene Region. PLoS One 8:e75067 (2013). Read more (PubMed: 24069379) »

See 1 Publication for this product

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