小鼠Bile Acid Receptor NR1H4肽(ab39820)

概述

描述

  • 性质
    Synthetic
  • 氨基酸序列
    • 种属
      Mouse
    • 序列
      RKNVKQHADQTVNED
    • 氨基酸
      244 to 238

相关产品

技术指标

Our Abpromise guarantee covers the use of ab39820 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Blocking - Blocking peptide for Anti-Bile Acid Receptor NR1H4 antibody (ab28480)

    Neutralising

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

常规信息

  • 别名
    • BAR
    • Bile acid receptor
    • Farnesoid X activated receptor
    • Farnesoid X receptor
    • Farnesoid X-activated receptor
    • Farnesol receptor HRR 1
    • Farnesol receptor HRR-1
    • Farnesol receptor HRR1
    • FXR
    • HRR 1
    • HRR1
    • NR1H4
    • NR1H4_HUMAN
    • Nuclear receptor subfamily 1 group H member 4
    • Retinoid X receptor interacting protein 14
    • Retinoid X receptor-interacting protein 14
    • RIP 14
    • RIP14
    • RXR interacting protein 14
    • RXR-interacting protein 14
    see all
  • 功能
    Ligand-activated transcription factor. Receptor for bile acids such as chenodeoxycholic acid, lithocholic acid and deoxycholic acid. Represses the transcription of the cholesterol 7-alpha-hydroxylase gene (CYP7A1) through the induction of NR0B2 or FGF19 expression, via two distinct mechanisms. Activates the intestinal bile acid-binding protein (IBABP). Activates the transcription of bile salt export pump ABCB11 by directly recruiting histone methyltransferase CARM1 to this locus.
  • 序列相似性
    Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 细胞定位
    Nucleus.
  • Information by UniProt

文献

ab39820 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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