Anti-Mortality Factor 4 like 2抗体(ab49184)


  • 产品名称Anti-Mortality Factor 4 like 2抗体
    参阅全部 Mortality Factor 4 like 2 一抗
  • 描述
    兔多克隆抗体to Mortality Factor 4 like 2
  • 特异性This antibody recognizes Mortality Factor 4 like 2
  • 经测试应用适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat, Cow, Dog, Chimpanzee
  • 免疫原

    A region within synthetic peptide: ASSGKKTAGP QQKNLEPALP GRWGGRSAEN PPSGSVRKTR KNKQKTPGNG, corresponding to N terminal amino acids 37-86 of Human Mortality Factor 4 like 2

  • 阳性对照
    • Human brain, fetal brain lysate.


Our Abpromise guarantee covers the use of ab49184 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.2 µg/ml. Detects a band of approximately 32 kDa (predicted molecular weight: 32 kDa). Good results were obtained when blocked with 5% non-fat dry milk in 0.05% PBS-T.
IHC-P Use a concentration of 4 - 8 µg/ml.
ELISA Use at an assay dependent concentration.

ELISA titre using peptide based assay was 1:1562500.


  • 功能Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
  • 序列相似性Belongs to the MRG family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA0026 antibody
    • MO4L2_HUMAN antibody
    • MORF related gene X protein antibody
    • MORF-related gene X protein antibody
    • Morf4l2 antibody
    • MORFL2 antibody
    • Mortality factor 4 like protein 2 antibody
    • Mortality factor 4-like protein 2 antibody
    • MRGX antibody
    • MSL3 2 protein antibody
    • Protein MSL3-2 antibody
    • Transcription factor like protein MRGX antibody
    • Transcription factor-like protein MRGX antibody
    see all

Anti-Mortality Factor 4 like 2 antibody 图像

  • Anti-Mortality Factor 4 like 2 antibody (ab49184) at 0.2 µg/ml + Fetal brain lysate at 10 µg with 5% skim milk in PBS.

    HRP conjugated anti-Rabbit IgG at 1/50000 dilution

    Predicted band size : 32 kDa
    Observed band size : 32 kDa
    Gel concentration: 12%
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of human brain tissue labelling Mortality Factor 4 like 2 with ab49184 at 4-8µg/ml. Arrows indicate positvely labelled neural cells. Magnification: x400.

Anti-Mortality Factor 4 like 2 antibody (ab49184)参考文献

ab49184 has not yet been referenced specifically in any publications.

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