Anti-Mortality Factor 4 like 2抗体(ab123581)

概述

  • 产品名称Anti-Mortality Factor 4 like 2抗体
    参阅全部 Mortality Factor 4 like 2 一抗
  • 描述
    兔多克隆抗体to Mortality Factor 4 like 2
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within C terminal amino acids 258-288 of Human Mortality Factor 4 like 2 (NP_001135901.1, NP_001135891.1, NP_001135898.1).

  • 阳性对照
    • 293 cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab123581 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 32 kDa.

靶标

  • 功能Component of the NuA4 histone acetyltransferase complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome - DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. The NuA4 complex ATPase and helicase activities seem to be, at least in part, contributed by the association of RUVBL1 and RUVBL2 with EP400. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage. Also component of the MSIN3A complex which acts to repress transcription by deacetylation of nucleosomal histones.
  • 序列相似性Belongs to the MRG family.
  • 细胞定位Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • KIAA0026 antibody
    • MO4L2_HUMAN antibody
    • MORF related gene X protein antibody
    • MORF-related gene X protein antibody
    • Morf4l2 antibody
    • MORFL2 antibody
    • Mortality factor 4 like protein 2 antibody
    • Mortality factor 4-like protein 2 antibody
    • MRGX antibody
    • MSL3 2 protein antibody
    • Protein MSL3-2 antibody
    • Transcription factor like protein MRGX antibody
    • Transcription factor-like protein MRGX antibody
    see all

Anti-Mortality Factor 4 like 2 antibody 图像

  • Anti-Mortality Factor 4 like 2 antibody (ab123581) at 1/100 dilution + 293 cell line lysate at 35 µg

    Predicted band size : 32 kDa

Anti-Mortality Factor 4 like 2 antibody (ab123581)参考文献

ab123581 has not yet been referenced specifically in any publications.

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