概述

  • 产品名称Anti-Morphine抗体
    参阅全部 Morphine 一抗
  • 描述
    小鼠单克隆抗体to Morphine
  • 特异性This antibody has a Kd of 2 nM for morphine and related alkaloids (e.g., codeine, nalorphine, andnaltrexone).
  • 经测试应用适用于: ELISAmore details
  • 免疫原

    Morphine conjugated at the C6 position to bovine serum albumin.

性能

应用

Our Abpromise guarantee covers the use of ab1060 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ELISA
  • 应用说明Dilute in PBS or medium which is identical to that used in the assay system.
    This antibody may be used inimmunoassays for detection of alkaloid/narcotic drugs
  • 靶标

    • 相关性Morphine is thought to produce reinforcement phenomena via stimulation of mu, delta, and kappa opioid receptors that regulate stress perception, pain control, reward behavior, and neurohormone secretion in reward-relevant brain systems. It has the highest affinity for mu, followed by delta and kappa. Rapid activation of the mu opioid receptor by morphine results in a euphoric phenotype, thus conferring the reinforcing effects of the drug. This activation is accompanied by extracellular dopamine release, which alters several events related to the cAMP signal transduction pathway. Of particular significance is that CREB seems to be modified by morphine, thereby affecting addictive behavioral phenomena, such as withdrawal symptoms.
    • 别名
      • Morphine 6 antibody

    Anti-Morphine antibody (ab1060)参考文献

    This product has been referenced in:
    • Torres OB  et al. A simple nonradioactive method for the determination of the binding affinities of antibodies induced by hapten bioconjugates for drugs of abuse. Anal Bioanal Chem 408:1191-204 (2016). Read more (PubMed: 26677020) »

    See 1 Publication for this product

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