Anti-Monocyte + Macrophage抗体[MOMA-2] (ab33451)
Key features and details
- Rat monoclonal [MOMA-2] to Monocyte + Macrophage
- Suitable for: IHC-Fr, IHC-P, IHC-FoFr, Flow Cyt
- Reacts with: Mouse
- Isotype: IgG2b
概述
-
产品名称
Anti-Monocyte + Macrophage抗体[MOMA-2] -
描述
大鼠单克隆抗体[MOMA-2] to Monocyte + Macrophage -
宿主
Rat -
特异性
This antibody recognises an intracellular antigen of mouse macrophages and monocytes. It reacts strongly with macrophages in lymphoid organs in all mouse strains tested. Staining may also be seen on the epithelium of mucosa.
-
经测试应用
适用于: IHC-Fr, IHC-P, IHC-FoFr, Flow Cytmore details -
种属反应性
与反应: Mouse -
免疫原
Tissue, cells or virus corresponding to Mouse Monocyte + Macrophage. Mouse lymph node stroma.
-
常规说明
The Life Science industry has been in the grips of a reproducibility crisis for a number of years. Abcam is leading the way in addressing this with our range of recombinant monoclonal antibodies and knockout edited cell lines for gold-standard validation. Please check that this product meets your needs before purchasing.
If you have any questions, special requirements or concerns, please send us an inquiry and/or contact our Support team ahead of purchase. Recommended alternatives for this product can be found below, along with publications, customer reviews and Q&As
性能
-
形式
Liquid -
存放说明
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. -
存储溶液
Preservative: 0.09% Sodium azide -
Concentration information loading...
-
纯度
Protein G purified -
克隆
单克隆 -
克隆编号
MOMA-2 -
同种型
IgG2b -
研究领域
相关产品
-
Compatible Secondaries
-
Conjugation kits
-
Isotype control
应用
The Abpromise guarantee
Abpromise™承诺保证使用ab33451于以下的经测试应用
“应用说明”部分 下显示的仅为推荐的起始稀释度;实际最佳的稀释度/浓度应由使用者检定。
应用 | Ab评论 | 说明 |
---|---|---|
IHC-Fr | (2) |
Use at an assay dependent concentration.
|
IHC-P |
Use at an assay dependent concentration. PubMed: 24449804
|
|
IHC-FoFr | (1) |
Use at an assay dependent concentration.
|
Flow Cyt |
Use at an assay dependent concentration.
Membrane permeabilisation is required for this application. ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
说明 |
---|
IHC-Fr
Use at an assay dependent concentration. |
IHC-P
Use at an assay dependent concentration. PubMed: 24449804 |
IHC-FoFr
Use at an assay dependent concentration. |
Flow Cyt
Use at an assay dependent concentration. Membrane permeabilisation is required for this application. ab18536 - Rat monoclonal IgG2b, is suitable for use as an isotype control with this antibody. |
靶标
-
相关性
Monocyte and macrophage are white blood cells that roam the body tissues engulfing foreign organisms. A monocyte is a leukocyte, part of the human body's immune system that protects against blood-borne pathogens and moves quickly (aprox. 8-12 hours) to sites of infection in the tissues. Monocytes are usually identified in stained smears by their large bi-lobed nucleus. Macrophages are cells within the tissues that originate from specific white blood cells called monocytes. Monocytes and macrophages are phagocytes, acting in both nonspecific defense (or innate immunity) as well as specific defense (or cell-mediated immunity) of vertebrate animals. Their role is to phagocytize (engulf and then digest) cellular debris and pathogens either as stationary or mobile cells, and to stimulate lymphocytes and other immune cells to respond to the pathogen. -
别名
- Macrophages antibody
- Monocytes antibody
数据表及文件
-
SDS download
-
Datasheet download
文献 (92)
ab33451 被引用在 92 文献中.
- Li Z et al. Astragali Radix-Coptis Rhizoma Herb Pair Attenuates Atherosclerosis in ApoE-/- Mice by Regulating the M1/M2 and Th1/Th2 Immune Balance and Activating the STAT6 Signaling Pathway. Evid Based Complement Alternat Med 2022:7421265 (2022). PubMed: 35178108
- Sun S et al. Adenosine Kinase Inhibition Prevents Severe Acute Pancreatitis via Suppressing Inflammation and Acinar Cell Necroptosis. Front Cell Dev Biol 10:827714 (2022). PubMed: 35281076
- Qi Y et al. Tongxinluo May Alleviate Inflammation and Improve the Stability of Atherosclerotic Plaques by Changing the Intestinal Flora. Front Pharmacol 13:805266 (2022). PubMed: 35431939
- Iwamoto M et al. The sodium-glucose co-transporter 2 inhibitor tofogliflozin suppresses atherosclerosis through glucose lowering in ApoE-deficient mice with streptozotocin-induced diabetes. Pharmacol Res Perspect 10:e00971 (2022). PubMed: 35707828
- Lin CW et al. Restoring Prohealing/Remodeling-Associated M2a/c Macrophages Using ON101 Accelerates Diabetic Wound Healing. JID Innov 2:100138 (2022). PubMed: 36017415