概述

  • 产品名称Anti-Monoamine Oxidase A抗体
    参阅全部 Monoamine Oxidase A 一抗
  • 描述
    山羊多克隆抗体to Monoamine Oxidase A
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
    预测可用于: Chimpanzee, Gorilla
  • 免疫原

    Synthetic peptide:

    C-DAPWEAQHADKWDK

    , corresponding to Internal sequence amino acids 141-154 of Human Monoamine Oxidase A

  • 阳性对照
    • Human heart lysate and transfected HEK293 cells transiently expressing Monoamine Oxidase A.

性能

应用

Our Abpromise guarantee covers the use of ab40835 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.1 - 0.3 µg/ml. Detects a band of approximately 70 kDa (predicted molecular weight: 60 kDa).

靶标

  • 功能Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOA preferentially oxidizes biogenic amines such as 5-hydroxytryptamine (5-HT), norepinephrine and epinephrine.
  • 组织特异性Heart, liver, duodenum, blood vessels and kidney.
  • 疾病相关Defects in MAOA are the cause of Brunner syndrome (BRUNS) [MIM:300615]. Brunner syndrome is a form of X-linked non-dysmorphic mild mental retardation. Male patients are affected by a syndrome of borderline mental retardation and exhibit abnormal behavior, including disturbed regulation of impulsive aggression. Obligate female carriers have normal intelligence and behavior.
  • 序列相似性Belongs to the flavin monoamine oxidase family.
  • 细胞定位Mitochondrion outer membrane.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Amine oxidase [flavin containing] A antibody
    • Amine oxidase [flavin-containing] A antibody
    • AOFA antibody
    • AOFA_HUMAN antibody
    • EC 1.4.3.4 antibody
    • MAO A antibody
    • MAO-A antibody
    • maoA antibody
    • Monoamine oxidase A antibody
    • Monoamine oxidase type A antibody
    see all

Anti-Monoamine Oxidase A antibody 图像

  • All lanes : Anti-Monoamine Oxidase A antibody (ab40835) at 0.3 µg/ml

    Lane 1 : Human heart lysate
    Lane 2 : Human heart lysate with immunising peptide

    Lysates/proteins at 35 µg per lane.

    Developed using the ECL technique

    Predicted band size : 60 kDa
    Observed band size : 70 kDa (why is the actual band size different from the predicted?)
    Additional bands at : 85 kDa (possible non-specific binding).
  • Anti-Monoamine Oxidase A antibody (ab40835) at 0.3 µg/ml + lysate prepared from transfected HEK293 cells transiently expressing Monoamine Oxidase A

    Predicted band size : 60 kDa
    Observed band size : 60 kDa
    Additional bands at : 180 kDa. We are unsure as to the identity of these extra bands.

Anti-Monoamine Oxidase A antibody (ab40835)参考文献

This product has been referenced in:
  • Kavazis AN  et al. Exercise training induces a cardioprotective phenotype and alterations in cardiac subsarcolemmal and intermyofibrillar mitochondrial proteins. Am J Physiol Heart Circ Physiol 297:H144-52 (2009). Read more (PubMed: 19429812) »

See 1 Publication for this product

Product Wall

There are currently no Abreviews or Questions for ab40835.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"