概述

  • 产品名称Anti-MOCS3抗体
    参阅全部 MOCS3 一抗
  • 描述
    小鼠单克隆抗体to MOCS3
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Recombinant full length protein, corresponding to amino acids 1-461 of Human MOCS3

性能

应用

Our Abpromise guarantee covers the use of ab57229 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB
  • 应用说明WB: Use at a concentration of 1-5 µg/ml.


    Not yet tested in other applications.
    Optimal dilutions/concentrations should be determined by the end user.
  • 靶标

    • 功能Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers URM1 and MOCS2A. Its N-terminus first activates URM1 and MOCS2A as acyl-adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 and MOCS2A to form thiocarboxylation (-COSH) of their C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1 and MOCS2A. Subsequently, a transient disulfide bond is formed. Does not use thiosulfate as sulfur donor; NFS1 probably acting as a sulfur donor for thiocarboxylation reactions.
    • 通路tRNA modification; 5-methoxycarbonylmethyl-2-thiouridine-tRNA biosynthesis.
      Cofactor biosynthesis; molybdopterin biosynthesis.
    • 序列相似性In the N-terminal section; belongs to the hesA/moeB/thiF family. UBA4 subfamily.
      Contains 1 rhodanese domain.
    • 细胞定位Cytoplasm > cytosol.
    • Information by UniProt
    • 数据库链接
    • 别名
      • Adenylyltransferase MOCS3 antibody
      • dJ914P20.3 antibody
      • MGC9252 antibody
      • MOCS 3 antibody
      • MOCS3 antibody
      • MOCS3_HUMAN antibody
      • Molybdenum cofactor synthesis 3 antibody
      • Molybdenum cofactor synthesis protein 3 antibody
      • Molybdopterin synthase sulfurylase antibody
      • Molybdopterin-synthase sulfurtransferase antibody
      • MPT synthase sulfurylase antibody
      • Sulfur carrier protein MOCS2A adenylyltransferase antibody
      • Sulfur carrier protein MOCS2A sulfurtransferase antibody
      • Sulfurtransferase MOCS3 antibody
      • UBA 4 antibody
      • UBA4 ubiquitin activating enzyme E1 homolog antibody
      • UBA4 antibody
      see all

    Anti-MOCS3 antibody 图像



    • Predicted band size : 50 kDa
      MOCS3 antibody (ab57229) at 1ug/lane + HeLa cell lysate at 25ug/lane.

    Anti-MOCS3 antibody (ab57229)参考文献

    ab57229 has not yet been referenced specifically in any publications.

    Product Wall

    There are currently no Abreviews or Questions for ab57229.
    Please use the links above to contact us or submit feedback about this product.

    Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"