概述

  • 产品名称Anti-MNK1抗体
    参阅全部 MNK1 一抗
  • 描述
    兔多克隆抗体to MNK1
  • 经测试应用适用于: IHC-Pmore details
  • 种属反应性
    与反应: Human
    预测可用于: Mouse, Rat
  • 免疫原

    Synthetic peptide derived from Internal region of Human MNK1.

  • 阳性对照
    • Human breast carcinoma tissue

性能

应用

Our Abpromise guarantee covers the use of ab111292 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
IHC-P 1/50 - 1/100. Perform heat mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.

靶标

  • 功能May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
  • 组织特异性Ubiquitous.
  • 序列相似性Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • 翻译后修饰Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase.
  • 细胞定位Cytoplasm and Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MAP kinase interacting kinase 1 antibody
    • MAP kinase interacting serine/threonine kinase 1 antibody
    • MAP kinase signal integrating kinase 1 antibody
    • MAP kinase signal-integrating kinase 1 antibody
    • MAP kinase-interacting serine/threonine-protein kinase 1 antibody
    • MAPK signal integrating kinase 1 antibody
    • MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody
    • mknk1 antibody
    • MKNK1_HUMAN antibody
    • MNK 1 antibody
    • Mnk1 antibody
    see all

Anti-MNK1 antibody 图像

  • Immunohistochemistry analysis of paraffin-embedded Human breast carcinoma tissue, using ab111292 at a dilution of 1/50. Left panel shows staining without immunizing peptide right panel shows staining with immunizing peptide

Anti-MNK1 antibody (ab111292)参考文献

ab111292 has not yet been referenced specifically in any publications.

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