Anti-MNK1抗体[24C2] (ab70834)

概述

  • 产品名称
    Anti-MNK1抗体[24C2]
    参阅全部 MNK1 一抗
  • 描述
    小鼠单克隆抗体[24C2] to MNK1
  • 经测试应用
    适用于: ChIP, WB, ELISAmore details
  • 种属反应性
    与反应: Mouse, Rat, Human
  • 免疫原

    Recombinant human protein purified from E.coli (His-MNK1 1-362 a.a.)

  • 阳性对照
    • HeLa cell lysate
  • 常规说明

    This product was changed from ascites to tissue culture supernatant on 18th September 2017. Lot numbers higher than GR284773 will be from tissue culture supernatant. Please note that the dilutions may need to be adjusted accordingly.

    Abcam is committed to meeting high standards of ethical manufacturing and as such, we will be discontinuing this product, which has been generated by the ascites method, within the next year. We are sorry for any inconvenience this may cause. If you would like help finding an alternative product, please do not hesitate to contact our scientific support team.

性能

应用

Our Abpromise guarantee covers the use of ab70834 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
ChIP Use at an assay dependent concentration.
WB Use a concentration of 4 µg/ml. Predicted molecular weight: 51 kDa.
ELISA Use at an assay dependent concentration.

靶标

  • 功能
    May play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap.
  • 组织特异性
    Ubiquitous.
  • 序列相似性
    Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Dual phosphorylation of Thr-250 and Thr-255 activates the kinase. Phosphorylation of Thr-385 activates the kinase.
  • 细胞定位
    Cytoplasm and Cytoplasm. Nucleus.
  • Information by UniProt
  • 数据库链接
  • 别名
    • MAP kinase interacting kinase 1 antibody
    • MAP kinase interacting serine/threonine kinase 1 antibody
    • MAP kinase signal integrating kinase 1 antibody
    • MAP kinase signal-integrating kinase 1 antibody
    • MAP kinase-interacting serine/threonine-protein kinase 1 antibody
    • MAPK signal integrating kinase 1 antibody
    • MITOGEN-ACTIVATED PROTEIN KINASE-INTERACTING SERINE/THREONINE KINASE 1 antibody
    • mknk1 antibody
    • MKNK1_HUMAN antibody
    • MNK 1 antibody
    • Mnk1 antibody
    see all

图片

  • All lanes : Anti-MNK1 antibody [24C2] (ab70834) at 1/1000 dilution

    Lane 1 : HeLa cell lysate
    Lane 2 : MCF-7 cell lysate
    Lane 3 : NIH3T3 cell lysate
    Lane 4 : H9C2 cell lysate


    Predicted band size : 51 kDa

实验方案

文献

ab70834 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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