概述

  • 产品名称
  • 描述
    山羊多克隆抗体to MMP7
  • 经测试应用
    适用于: WB, IHC-P, ELISAmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide:

    QKLYGKRSNSRKK

    conjugated to KLH, corresponding to C terminal amino acids 255-267 of Human MMP7.

  • 阳性对照
    • Human uterus tissue; Human breast lysate

性能

应用

Our Abpromise guarantee covers the use of ab112017 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 0.03 - 0.1 µg/ml. Predicted molecular weight: 30 kDa.
IHC-P Use a concentration of 3.75 µg/ml.
ELISA 1/64000.

靶标

  • 功能
    Degrades casein, gelatins of types I, III, IV, and V, and fibronectin. Activates procollagenase.
  • 序列相似性
    Belongs to the peptidase M10A family.
  • 结构域
    The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 细胞定位
    Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Matrilysin antibody
    • Matrin antibody
    • Matrix Metalloproteinase 7 antibody
    • Matrix metalloproteinase-7 antibody
    • MMP 7 antibody
    • MMP-7 antibody
    • MMP7 antibody
    • MMP7_HUMAN antibody
    • MPSL1 antibody
    • PUMP 1 antibody
    • Pump 1 protease antibody
    • Pump-1 protease antibody
    • PUMP1 antibody
    • Uterine matrilysin antibody
    • Uterine metalloproteinase antibody
    see all

Anti-MMP7 antibody 图像

  • Immunohistochemical analysis of MMP7 expression in formalin-fixed, paraffin-embedded Human uterus using ab112017 at 3.75 µg/ml.
  • Anti-MMP7 antibody (ab112017) at 0.03 µg/ml + Human breast lysate (in RIPA buffer) at 35 µg

    Predicted band size : 30 kDa

Anti-MMP7 antibody (ab112017)参考文献

ab112017 has not yet been referenced specifically in any publications.

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