Anti-MMP3抗体[SL-1 ID3] (ab3204)

概述

  • 产品名称Anti-MMP3抗体[SL-1 ID3]
    参阅全部 MMP3 一抗
  • 描述
    小鼠单克隆抗体[SL-1 ID3] to MMP3
  • 特异性ab3204 reacts with both pro and active forms of MMP 3.
  • 经测试应用适用于: WB, ICC/IFmore details
    不适用于: IHC-P
  • 种属反应性
    与反应: Human
  • 免疫原

    APMA (4 Aminophenylmercuric acetate) activated Human stromelysin 1 (SL 1).

  • 阳性对照
    • Conditioned serum-free medium from TPA treated human Endometrial cells.

应用

Our Abpromise guarantee covers the use of ab3204 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB Use a concentration of 2 - 4 µg/ml. Predicted molecular weight: 54 kDa. Incubate for 2 hours at room temperature.
ICC/IF Use at an assay dependent concentration.
  • 应用说明Is unsuitable for IHC-P.
  • 靶标

    • 功能Can degrade fibronectin, laminin, gelatins of type I, III, IV, and V; collagens III, IV, X, and IX, and cartilage proteoglycans. Activates procollagenase.
    • 序列相似性Belongs to the peptidase M10A family.
      Contains 4 hemopexin-like domains.
    • 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
    • 细胞定位Secreted > extracellular space > extracellular matrix.
    • Information by UniProt
    • 数据库链接
    • 别名
      • CHDS6 antibody
      • Matrix metalloproteinase 3 antibody
      • Matrix metalloproteinase-3 antibody
      • MGC126102 antibody
      • MGC126103 antibody
      • MGC126104 antibody
      • MMP 3 antibody
      • MMP-3 antibody
      • MMP3 antibody
      • MMP3_HUMAN antibody
      • Proteoglycanase antibody
      • SL-1 antibody
      • SL1 antibody
      • STMY antibody
      • STMY1 antibody
      • STR1 antibody
      • Stromelysin 1 antibody
      • Stromelysin-1 antibody
      • Transin 1 antibody
      • Transin-1 antibody
      see all

    Anti-MMP3 antibody [SL-1 ID3] (ab3204)参考文献

    ab3204 has not yet been referenced specifically in any publications.

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