概述

  • 产品名称Anti-MMP28抗体
    参阅全部 MMP28 一抗
  • 描述
    兔多克隆抗体to MMP28
  • 经测试应用适用于: WBmore details
  • 种属反应性
    与反应: Human
  • 免疫原

    Synthetic peptide conjugated to KLH, corresponding to a region within internal sequence amino acids 194-223 of Human MMP28 (NP_001027449.1, NP_077278.1).

  • 阳性对照
    • MDA-MB435 cell line lysate.

性能

应用

Our Abpromise guarantee covers the use of ab116580 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

应用 Ab评论 说明
WB 1/100 - 1/500. Predicted molecular weight: 59 kDa.

靶标

  • 功能Can degrade casein. Could play a role in tissues homeostasis and repair.
  • 组织特异性Expressed at high levels in testes and lung. Low levels are detected in kidney, pancreas and skin. Also expressed in fetal lung, brain, skeletal muscle and kidney. Expressed selectively in keratinocytesis. Widely expressed in several carcinomas as well. Is up-regulated in response to injury in the skin.
  • 序列相似性Belongs to the peptidase M10A family.
    Contains 4 hemopexin-like domains.
  • 结构域The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion, thus inhibiting the enzyme. The dissociation of the cysteine from the zinc ion upon the activation-peptide release activates the enzyme.
  • 翻译后修饰The precursor is cleaved by a furin endopeptidase.
  • 细胞定位Secreted > extracellular space > extracellular matrix.
  • Information by UniProt
  • 数据库链接
  • 别名
    • Epilysin antibody
    • Matrix metalloproteinase 28 antibody
    • Matrix metalloproteinase-28 antibody
    • MM 28 antibody
    • MM28 antibody
    • MMP 25 antibody
    • MMP 28 antibody
    • MMP-28 antibody
    • MMP25 antibody
    • MMP28 antibody
    • MMP28_HUMAN antibody
    see all

Anti-MMP28 antibody 图像

  • Anti-MMP28 antibody (ab116580) at 1/100 dilution + MDA-MB435 cell line lysate at 35 µg

    Predicted band size : 59 kDa

Anti-MMP28 antibody (ab116580)参考文献

ab116580 has not yet been referenced specifically in any publications.

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